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- W2974143954 abstract "The term access to medicines was, until a few years ago, associated with the discussion surrounding cheaper (generic) vital drugs (HIV, tuberculosis, etc.) in developing countries. For some time, Western countries and institutions (OECD, European Commission, etc.) have also begun to focus on access to medicines in an attempt to counteract unsustainable drug prices. Expenditure on research and development (R&D) is mostly used by manufacturers as a justification for high prices. The real -resource consuming and high risk- basic research takes place mainly in the public sector (in universities and corresponding publicly funded research institutions) instead. Little publicised knowledge on public spending, however, exists so far. The project objective is to collect information on public contributions to drug research and development and thus contribute to the discussion on Return on Investment of Public Investment. The project was carried out in two stages: in Phase 1, a methodology (search strategy and sources) was developed to systematically identify the contribution of public research funding to the development of new drugs. In Phase 2, the methodology of the Phase 1 analytical approach was piloted using three selected paediatric Orphan Drugs (Spinraza®, Brineura®, Crysvita®), which were approved by the European Medicines Agency (EMA) in 2017. The research on public and philanthropic RD the results vary greatly. Further piloting such as a refinement of the search strategy is underway." @default.
- W2974143954 created "2019-09-26" @default.
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- W2974143954 date "2019-09-01" @default.
- W2974143954 modified "2023-09-26" @default.
- W2974143954 title "Public & philanthropic financial contribution to the development of new drugs: Methodology & 3 Case Studies" @default.
- W2974143954 hasPublicationYear "2019" @default.
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