Matches in SemOpenAlex for { <https://semopenalex.org/work/W2974163978> ?p ?o ?g. }
- W2974163978 abstract "Abstract Zika virus (ZIKV) and dengue virus (DENV) are co-endemic in many parts of the world, but the impact of ZIKV infection on subsequent DENV infection is not well understood. Here we show in rhesus macaques that the time elapsed after ZIKV infection affects the immune response to DENV infection. We show that previous ZIKV exposure increases the magnitude of the antibody and T cell responses against DENV. The time interval between ZIKV and subsequent DENV infection further affects the immune response. A mid-convalescent period of 10 months after ZIKV infection results in higher and more durable antibody and T cell responses to DENV infection than a short period of 2 months. In contrast, previous ZIKV infection does not affect DENV viremia or pro-inflammatory status. Collectively, we find no evidence of a detrimental effect of ZIKV immunity in a subsequent DENV infection. This supports the implementation of ZIKV vaccines that could also boost immunity against future DENV epidemics." @default.
- W2974163978 created "2019-09-26" @default.
- W2974163978 creator A5005425522 @default.
- W2974163978 creator A5020572780 @default.
- W2974163978 creator A5027414873 @default.
- W2974163978 creator A5033936712 @default.
- W2974163978 creator A5042920740 @default.
- W2974163978 creator A5044391826 @default.
- W2974163978 creator A5044714552 @default.
- W2974163978 creator A5057313511 @default.
- W2974163978 creator A5062185231 @default.
- W2974163978 creator A5063730724 @default.
- W2974163978 creator A5065157313 @default.
- W2974163978 creator A5070688263 @default.
- W2974163978 creator A5071431150 @default.
- W2974163978 creator A5080801760 @default.
- W2974163978 creator A5083691880 @default.
- W2974163978 creator A5085490606 @default.
- W2974163978 creator A5088980896 @default.
- W2974163978 creator A5090036124 @default.
- W2974163978 date "2019-09-20" @default.
- W2974163978 modified "2023-10-14" @default.
- W2974163978 title "Time elapsed between Zika and dengue virus infections affects antibody and T cell responses" @default.
- W2974163978 cites W1785302422 @default.
- W2974163978 cites W1965853371 @default.
- W2974163978 cites W1968234422 @default.
- W2974163978 cites W1982342659 @default.
- W2974163978 cites W1983305047 @default.
- W2974163978 cites W2050818336 @default.
- W2974163978 cites W2053490656 @default.
- W2974163978 cites W2079295451 @default.
- W2974163978 cites W2081356962 @default.
- W2974163978 cites W2091264775 @default.
- W2974163978 cites W2100675371 @default.
- W2974163978 cites W2111222009 @default.
- W2974163978 cites W2126426353 @default.
- W2974163978 cites W2127567948 @default.
- W2974163978 cites W2131222241 @default.
- W2974163978 cites W2141264905 @default.
- W2974163978 cites W2156783779 @default.
- W2974163978 cites W2170806251 @default.
- W2974163978 cites W2171633892 @default.
- W2974163978 cites W2205335187 @default.
- W2974163978 cites W2222158372 @default.
- W2974163978 cites W2289704315 @default.
- W2974163978 cites W2402340060 @default.
- W2974163978 cites W2460107925 @default.
- W2974163978 cites W2464735068 @default.
- W2974163978 cites W2469258508 @default.
- W2974163978 cites W2470330280 @default.
- W2974163978 cites W2482332858 @default.
- W2974163978 cites W2505452802 @default.
- W2974163978 cites W2521741667 @default.
- W2974163978 cites W2529443144 @default.
- W2974163978 cites W2595707583 @default.
- W2974163978 cites W2600368028 @default.
- W2974163978 cites W2603610268 @default.
- W2974163978 cites W2605447488 @default.
- W2974163978 cites W2620298867 @default.
- W2974163978 cites W2673196552 @default.
- W2974163978 cites W2686440742 @default.
- W2974163978 cites W2714715604 @default.
- W2974163978 cites W2726796006 @default.
- W2974163978 cites W2734465900 @default.
- W2974163978 cites W2745067063 @default.
- W2974163978 cites W2752337702 @default.
- W2974163978 cites W2761760850 @default.
- W2974163978 cites W2767265855 @default.
- W2974163978 cites W2782552661 @default.
- W2974163978 cites W2793881639 @default.
- W2974163978 cites W2795840126 @default.
- W2974163978 cites W2797059991 @default.
- W2974163978 cites W2798061255 @default.
- W2974163978 cites W2803064139 @default.
- W2974163978 cites W2804325477 @default.
- W2974163978 cites W2884928200 @default.
- W2974163978 cites W2899451573 @default.
- W2974163978 cites W2899624540 @default.
- W2974163978 cites W2901065350 @default.
- W2974163978 cites W2907646662 @default.
- W2974163978 cites W2908608989 @default.
- W2974163978 cites W2914723032 @default.
- W2974163978 cites W2915041665 @default.
- W2974163978 cites W2943250306 @default.
- W2974163978 cites W2966749835 @default.
- W2974163978 cites W3022354856 @default.
- W2974163978 doi "https://doi.org/10.1038/s41467-019-12295-2" @default.
- W2974163978 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6754404" @default.
- W2974163978 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31541110" @default.
- W2974163978 hasPublicationYear "2019" @default.
- W2974163978 type Work @default.
- W2974163978 sameAs 2974163978 @default.
- W2974163978 citedByCount "24" @default.
- W2974163978 countsByYear W29741639782020 @default.
- W2974163978 countsByYear W29741639782021 @default.
- W2974163978 countsByYear W29741639782022 @default.
- W2974163978 countsByYear W29741639782023 @default.
- W2974163978 crossrefType "journal-article" @default.
- W2974163978 hasAuthorship W2974163978A5005425522 @default.
- W2974163978 hasAuthorship W2974163978A5020572780 @default.