FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2974198720> ?p ?o ?g. }

• W2974198720 endingPage "2777" @default.
• W2974198720 startingPage "2763" @default.
• W2974198720 abstract "Group 2 innate lymphoid cells (ILC2s) possess indispensable roles during type 2–mediated inflammatory diseases. Although their physiological and detrimental immune functions seem to depend on the anatomical compartment they reside, their tissue tropism and the molecular and immunological processes regulating the self-renewal of the local pool of ILC2s in the context of inflammation or infection are incompletely understood. Here, we analyzed the role of the CC-chemokine receptor CCR8 for the biological functions of ILC2s. In vitro and in vivo experiments indicated that CCR8 is in comparison to the related molecule CCR4 less important for migration of these cells. However, we found that activated mouse and human ILC2s produce the CCR8 ligand CCL1 and are a major source of CCL1 in vivo. CCL1 signaling to ILC2s regulates their proliferation and supports their capacity to protect against helminthic infections. In summary, we identify a novel chemokine receptor–dependent mechanism by which ILC2s are regulated during type 2 responses." @default.
• W2974198720 created "2019-09-26" @default.
• W2974198720 creator A5003042131 @default.
• W2974198720 creator A5012131250 @default.
• W2974198720 creator A5016845388 @default.
• W2974198720 creator A5018818042 @default.
• W2974198720 creator A5027340443 @default.
• W2974198720 creator A5032480207 @default.
• W2974198720 creator A5034457503 @default.
• W2974198720 creator A5052806458 @default.
• W2974198720 creator A5065672260 @default.
• W2974198720 date "2019-09-19" @default.
• W2974198720 modified "2023-10-17" @default.
• W2974198720 title "A CCL1/CCR8-dependent feed-forward mechanism drives ILC2 functions in type 2–mediated inflammation" @default.
• W2974198720 cites W1485171755 @default.
• W2974198720 cites W1640181718 @default.
• W2974198720 cites W1873569416 @default.
• W2974198720 cites W1893012437 @default.
• W2974198720 cites W1903818764 @default.
• W2974198720 cites W1976026025 @default.
• W2974198720 cites W1976414811 @default.
• W2974198720 cites W1995070836 @default.
• W2974198720 cites W1997535189 @default.
• W2974198720 cites W1997883939 @default.
• W2974198720 cites W2002307060 @default.
• W2974198720 cites W2003604887 @default.
• W2974198720 cites W2009357776 @default.
• W2974198720 cites W2014320172 @default.
• W2974198720 cites W2014540704 @default.
• W2974198720 cites W2015692753 @default.
• W2974198720 cites W2038846887 @default.
• W2974198720 cites W2042083424 @default.
• W2974198720 cites W2043133666 @default.
• W2974198720 cites W2047088156 @default.
• W2974198720 cites W2047882259 @default.
• W2974198720 cites W2081155954 @default.
• W2974198720 cites W2082624887 @default.
• W2974198720 cites W2089685608 @default.
• W2974198720 cites W2096545973 @default.
• W2974198720 cites W2099703514 @default.
• W2974198720 cites W2101436464 @default.
• W2974198720 cites W2102873430 @default.
• W2974198720 cites W2104466526 @default.
• W2974198720 cites W2111115131 @default.
• W2974198720 cites W2114962227 @default.
• W2974198720 cites W2121376255 @default.
• W2974198720 cites W2130364297 @default.
• W2974198720 cites W2130509509 @default.
• W2974198720 cites W2136267701 @default.
• W2974198720 cites W2140206763 @default.
• W2974198720 cites W2145818079 @default.
• W2974198720 cites W2152222824 @default.
• W2974198720 cites W2170737790 @default.
• W2974198720 cites W2182536415 @default.
• W2974198720 cites W2210206421 @default.
• W2974198720 cites W2235170711 @default.
• W2974198720 cites W2266367473 @default.
• W2974198720 cites W2278683490 @default.
• W2974198720 cites W2300527575 @default.
• W2974198720 cites W2471110308 @default.
• W2974198720 cites W2499712993 @default.
• W2974198720 cites W2576968561 @default.
• W2974198720 cites W2602458551 @default.
• W2974198720 cites W2619366202 @default.
• W2974198720 cites W2727087240 @default.
• W2974198720 cites W2773338109 @default.
• W2974198720 cites W2782130265 @default.
• W2974198720 cites W2796222443 @default.
• W2974198720 cites W2810444722 @default.
• W2974198720 cites W2888376450 @default.
• W2974198720 cites W2889454624 @default.
• W2974198720 cites W2936843255 @default.
• W2974198720 cites W2948086147 @default.
• W2974198720 doi "https://doi.org/10.1084/jem.20182111" @default.
• W2974198720 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6888976" @default.
• W2974198720 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31537642" @default.
• W2974198720 hasPublicationYear "2019" @default.
• W2974198720 type Work @default.
• W2974198720 sameAs 2974198720 @default.
• W2974198720 citedByCount "38" @default.
• W2974198720 countsByYear W29741987202019 @default.
• W2974198720 countsByYear W29741987202020 @default.
• W2974198720 countsByYear W29741987202021 @default.
• W2974198720 countsByYear W29741987202022 @default.
• W2974198720 countsByYear W29741987202023 @default.
• W2974198720 crossrefType "journal-article" @default.
• W2974198720 hasAuthorship W2974198720A5003042131 @default.
• W2974198720 hasAuthorship W2974198720A5012131250 @default.
• W2974198720 hasAuthorship W2974198720A5016845388 @default.
• W2974198720 hasAuthorship W2974198720A5018818042 @default.
• W2974198720 hasAuthorship W2974198720A5027340443 @default.
• W2974198720 hasAuthorship W2974198720A5032480207 @default.
• W2974198720 hasAuthorship W2974198720A5034457503 @default.
• W2974198720 hasAuthorship W2974198720A5052806458 @default.
• W2974198720 hasAuthorship W2974198720A5065672260 @default.
• W2974198720 hasBestOaLocation W29741987201 @default.
• W2974198720 hasConcept C111472728 @default.
• W2974198720 hasConcept C12823836 @default.

• next