FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2974556543> ?p ?o ?g. }

• W2974556543 endingPage "539" @default.
• W2974556543 startingPage "539" @default.
• W2974556543 abstract "Saxitoxin (STX) and its analogues, the potent voltage-gated sodium channel blockers, are biosynthesized by freshwater cyanobacteria and marine dinoflagellates. We previously identified several biosynthetic intermediates in the extract of the cyanobacterium, Anabaena circinalis (TA04), that are primarily produced during the early and middle stages in the biosynthetic pathway to produce STX. These findings allowed us to propose a putative biosynthetic pathway responsible for STX production based on the structures of these intermediates. In the present study, we identified 12β-deoxygonyautoxin 3 (12β-deoxyGTX3), a novel STX analogue produced by A. circinalis (TA04), by comparing the retention time and MS/MS fragmentation pattern with those of synthetic standards using LC–MS. The presence of this compound in A. circinalis (TA04) is consistent with stereoselective enzymatic oxidations at C11 and C12, and 11-O-sulfation, during the late stage of STX biosynthesis, as proposed in previous studies." @default.
• W2974556543 created "2019-09-26" @default.
• W2974556543 creator A5027654165 @default.
• W2974556543 creator A5032403727 @default.
• W2974556543 creator A5048373541 @default.
• W2974556543 creator A5059663164 @default.
• W2974556543 creator A5089622945 @default.
• W2974556543 date "2019-09-16" @default.
• W2974556543 modified "2023-10-16" @default.
• W2974556543 title "Identification of a Novel Saxitoxin Analogue, 12β-Deoxygonyautoxin 3, in the Cyanobacterium, Anabaena circinalis (TA04)" @default.
• W2974556543 cites W1889782681 @default.
• W2974556543 cites W1950083293 @default.
• W2974556543 cites W1964210708 @default.
• W2974556543 cites W1968775774 @default.
• W2974556543 cites W1972471260 @default.
• W2974556543 cites W2020344022 @default.
• W2974556543 cites W2027492187 @default.
• W2974556543 cites W2034165718 @default.
• W2974556543 cites W2036233390 @default.
• W2974556543 cites W2040995813 @default.
• W2974556543 cites W2042602537 @default.
• W2974556543 cites W2075251933 @default.
• W2974556543 cites W2082672547 @default.
• W2974556543 cites W2087090641 @default.
• W2974556543 cites W2092964100 @default.
• W2974556543 cites W2130192863 @default.
• W2974556543 cites W2134702315 @default.
• W2974556543 cites W2135056605 @default.
• W2974556543 cites W2152589735 @default.
• W2974556543 cites W2412354339 @default.
• W2974556543 cites W2472516462 @default.
• W2974556543 cites W2544119226 @default.
• W2974556543 cites W2602135398 @default.
• W2974556543 cites W2785412239 @default.
• W2974556543 cites W2890410714 @default.
• W2974556543 cites W2897365853 @default.
• W2974556543 cites W2901973801 @default.
• W2974556543 cites W2920963810 @default.
• W2974556543 cites W2937814869 @default.
• W2974556543 cites W2949313562 @default.
• W2974556543 cites W2965742803 @default.
• W2974556543 cites W4211157125 @default.
• W2974556543 doi "https://doi.org/10.3390/toxins11090539" @default.
• W2974556543 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6784053" @default.
• W2974556543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31527551" @default.
• W2974556543 hasPublicationYear "2019" @default.
• W2974556543 type Work @default.
• W2974556543 sameAs 2974556543 @default.
• W2974556543 citedByCount "11" @default.
• W2974556543 countsByYear W29745565432019 @default.
• W2974556543 countsByYear W29745565432020 @default.
• W2974556543 countsByYear W29745565432021 @default.
• W2974556543 countsByYear W29745565432022 @default.
• W2974556543 countsByYear W29745565432023 @default.
• W2974556543 crossrefType "journal-article" @default.
• W2974556543 hasAuthorship W2974556543A5027654165 @default.
• W2974556543 hasAuthorship W2974556543A5032403727 @default.
• W2974556543 hasAuthorship W2974556543A5048373541 @default.
• W2974556543 hasAuthorship W2974556543A5059663164 @default.
• W2974556543 hasAuthorship W2974556543A5089622945 @default.
• W2974556543 hasBestOaLocation W29745565431 @default.
• W2974556543 hasConcept C181199279 @default.
• W2974556543 hasConcept C2777367657 @default.
• W2974556543 hasConcept C2777530773 @default.
• W2974556543 hasConcept C2777646408 @default.
• W2974556543 hasConcept C2779669040 @default.
• W2974556543 hasConcept C2910844273 @default.
• W2974556543 hasConcept C523546767 @default.
• W2974556543 hasConcept C54355233 @default.
• W2974556543 hasConcept C553450214 @default.
• W2974556543 hasConcept C55493867 @default.
• W2974556543 hasConcept C86803240 @default.
• W2974556543 hasConcept C89423630 @default.
• W2974556543 hasConceptScore W2974556543C181199279 @default.
• W2974556543 hasConceptScore W2974556543C2777367657 @default.
• W2974556543 hasConceptScore W2974556543C2777530773 @default.
• W2974556543 hasConceptScore W2974556543C2777646408 @default.
• W2974556543 hasConceptScore W2974556543C2779669040 @default.
• W2974556543 hasConceptScore W2974556543C2910844273 @default.
• W2974556543 hasConceptScore W2974556543C523546767 @default.
• W2974556543 hasConceptScore W2974556543C54355233 @default.
• W2974556543 hasConceptScore W2974556543C553450214 @default.
• W2974556543 hasConceptScore W2974556543C55493867 @default.
• W2974556543 hasConceptScore W2974556543C86803240 @default.
• W2974556543 hasConceptScore W2974556543C89423630 @default.
• W2974556543 hasFunder F4320334764 @default.
• W2974556543 hasIssue "9" @default.
• W2974556543 hasLocation W29745565431 @default.
• W2974556543 hasLocation W29745565432 @default.
• W2974556543 hasLocation W29745565433 @default.
• W2974556543 hasLocation W29745565434 @default.
• W2974556543 hasLocation W29745565435 @default.
• W2974556543 hasLocation W29745565436 @default.
• W2974556543 hasOpenAccess W2974556543 @default.
• W2974556543 hasPrimaryLocation W29745565431 @default.
• W2974556543 hasRelatedWork W1139957301 @default.
• W2974556543 hasRelatedWork W192257739 @default.
• W2974556543 hasRelatedWork W1971435929 @default.

• next