FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2975152488> ?p ?o ?g. }

• W2975152488 endingPage "1487" @default.
• W2975152488 startingPage "1480" @default.
• W2975152488 abstract "Introduction Thrombocytopaenia and autoimmune haemolytic anaemia (AIHA) have considerable impact on prognosis in systemic lupus erythematosus (SLE). We investigated the frequencies of these haemocytopaenias, along with their associations and effect on outcome in a single-centre cohort of patients with SLE. Methods Demographic characteristics, clinical features, autoantibody profiles, damage and mortality data were compared between patients with and without each haematological abnormality. Variables displaying significant differences between the groups were entered into logistic regression. Results Ninety-three patients had AIHA and 215 had thrombocytopaenia. Both were associated with neuropsychiatric (NP) involvement, with each other, leucopaenia, antiphospholipid syndrome (APS) and antiphospholipid antibodies. More patients in both groups had organ damage, and their damage scores were higher. Association to NP damage was discernible. In addition, cardiovascular and renal damage and diabetes were more pronounced in patients with thrombocytopaenia. At logistic regression analysis, younger age, anticardiolipin antibody IgM positivity, leucopaenia and thrombocytopaenia were associated with AIHA whilst lupus anticoagulant activity, AIHA, leucopaenia, APS and NP involvement were associated with thrombocytopaenia. Among damage items, peripheral vascular damage, diabetes, NP damage, renal and ocular damage displayed significant associations with thrombocytopaenia, whereas none of the items did with AIHA. Patients with AIHA had significantly reduced survival rates at 10 and 20 years. Conclusions We observed that AIHA and thrombocytopaenia were associated with severe lupus, affecting major organs and causing end organ damage. Thus, they may be considered as prognostic markers. Furthermore, AIHA and especially thrombocytopaenia may also be a marker for a subgroup of lupus patients who have or may develop APS." @default.
• W2975152488 created "2019-10-03" @default.
• W2975152488 creator A5003591041 @default.
• W2975152488 creator A5004962865 @default.
• W2975152488 creator A5030875138 @default.
• W2975152488 creator A5033265098 @default.
• W2975152488 creator A5036218340 @default.
• W2975152488 creator A5056102369 @default.
• W2975152488 creator A5069531416 @default.
• W2975152488 creator A5086170092 @default.
• W2975152488 date "2019-09-26" @default.
• W2975152488 modified "2023-10-18" @default.
• W2975152488 title "Autoimmune haemolytic anaemia and thrombocytopaenia in a single-centre cohort of patients with systemic lupus erythematosus from Turkey: clinical associations and effect on disease damage and survival" @default.
• W2975152488 cites W157535844 @default.
• W2975152488 cites W1967862302 @default.
• W2975152488 cites W1969258378 @default.
• W2975152488 cites W1972408385 @default.
• W2975152488 cites W1979904797 @default.
• W2975152488 cites W1981501313 @default.
• W2975152488 cites W1988401043 @default.
• W2975152488 cites W1989329196 @default.
• W2975152488 cites W1990304726 @default.
• W2975152488 cites W1991659714 @default.
• W2975152488 cites W1997748320 @default.
• W2975152488 cites W1998761103 @default.
• W2975152488 cites W2027624699 @default.
• W2975152488 cites W2048667105 @default.
• W2975152488 cites W2054330426 @default.
• W2975152488 cites W2054743311 @default.
• W2975152488 cites W2055282464 @default.
• W2975152488 cites W2070527591 @default.
• W2975152488 cites W2078838686 @default.
• W2975152488 cites W2078860309 @default.
• W2975152488 cites W2080718497 @default.
• W2975152488 cites W2088340307 @default.
• W2975152488 cites W2107192733 @default.
• W2975152488 cites W2108905161 @default.
• W2975152488 cites W2120617664 @default.
• W2975152488 cites W2122253925 @default.
• W2975152488 cites W2122660238 @default.
• W2975152488 cites W2123933806 @default.
• W2975152488 cites W2131750992 @default.
• W2975152488 cites W2135762678 @default.
• W2975152488 cites W2136995416 @default.
• W2975152488 cites W2139886079 @default.
• W2975152488 cites W2139951436 @default.
• W2975152488 cites W2159860161 @default.
• W2975152488 cites W2166189661 @default.
• W2975152488 cites W2166419933 @default.
• W2975152488 cites W2478361503 @default.
• W2975152488 cites W3096053797 @default.
• W2975152488 doi "https://doi.org/10.1177/0961203319877245" @default.
• W2975152488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31558101" @default.
• W2975152488 hasPublicationYear "2019" @default.
• W2975152488 type Work @default.
• W2975152488 sameAs 2975152488 @default.
• W2975152488 citedByCount "7" @default.
• W2975152488 countsByYear W29751524882020 @default.
• W2975152488 countsByYear W29751524882021 @default.
• W2975152488 countsByYear W29751524882022 @default.
• W2975152488 countsByYear W29751524882023 @default.
• W2975152488 crossrefType "journal-article" @default.
• W2975152488 hasAuthorship W2975152488A5003591041 @default.
• W2975152488 hasAuthorship W2975152488A5004962865 @default.
• W2975152488 hasAuthorship W2975152488A5030875138 @default.
• W2975152488 hasAuthorship W2975152488A5033265098 @default.
• W2975152488 hasAuthorship W2975152488A5036218340 @default.
• W2975152488 hasAuthorship W2975152488A5056102369 @default.
• W2975152488 hasAuthorship W2975152488A5069531416 @default.
• W2975152488 hasAuthorship W2975152488A5086170092 @default.
• W2975152488 hasConcept C126322002 @default.
• W2975152488 hasConcept C134018914 @default.
• W2975152488 hasConcept C151956035 @default.
• W2975152488 hasConcept C159654299 @default.
• W2975152488 hasConcept C163764329 @default.
• W2975152488 hasConcept C203014093 @default.
• W2975152488 hasConcept C2775915377 @default.
• W2975152488 hasConcept C2776874634 @default.
• W2975152488 hasConcept C2776912625 @default.
• W2975152488 hasConcept C2779134260 @default.
• W2975152488 hasConcept C2780022809 @default.
• W2975152488 hasConcept C555293320 @default.
• W2975152488 hasConcept C71924100 @default.
• W2975152488 hasConcept C72563966 @default.
• W2975152488 hasConcept C90924648 @default.
• W2975152488 hasConceptScore W2975152488C126322002 @default.
• W2975152488 hasConceptScore W2975152488C134018914 @default.
• W2975152488 hasConceptScore W2975152488C151956035 @default.
• W2975152488 hasConceptScore W2975152488C159654299 @default.
• W2975152488 hasConceptScore W2975152488C163764329 @default.
• W2975152488 hasConceptScore W2975152488C203014093 @default.
• W2975152488 hasConceptScore W2975152488C2775915377 @default.
• W2975152488 hasConceptScore W2975152488C2776874634 @default.
• W2975152488 hasConceptScore W2975152488C2776912625 @default.
• W2975152488 hasConceptScore W2975152488C2779134260 @default.
• W2975152488 hasConceptScore W2975152488C2780022809 @default.
• W2975152488 hasConceptScore W2975152488C555293320 @default.
• W2975152488 hasConceptScore W2975152488C71924100 @default.

• next