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• W2975173501 endingPage "722" @default.
• W2975173501 startingPage "722" @default.
• W2975173501 abstract "Atrial fibrillation (AF) commonly occurs in patient with acute myocardial infarction (AMI). Potential triggers for AF development in this setting includes reduced left ventricular function, advanced diastolic dysfunction and mitral regurgitation leading to elevated left atrial pressures and atrial stretch. Other triggering mechanisms include inflammation and atrial ischemia. Multiple studies have shown that AF in patients with is associated with increased mortality. However, whether AF is a risk marker or a causal mediator of death remains controversial. There is relative dearth of data with regard to optimal management of AF in the setting of acute coronary syndromes. Patients with AMI who develop AF are at increased risk of stroke. However, the issue of the most appropriate antithrombotic regimens is complex given the need to balance stroke prevention against recurrent coronary events or stent thrombosis and the risk of bleeding. Presently, 'triple therapy' consisting of dual antiplatelet agents plus oral anticoagulants for 3-6 months or longer has been recommended for patients at moderate-high risk of stroke. Atrial fibrillation (AF), the most common sustained arrhythmia seen in clinical practice, often coincides with acute myocardial infarction (AMI), with a reported incidence ranging between 7% and 21%.[1] The development of atrial fibrillation in the acute phase of AMI may aggravate ischemia and heart failure, lead to clinical instability and adversely affect outcome. In the following we will review the pathophysiology, clinical characteristics and importance, and management of AF occurring in the setting of AMI." @default.
• W2975173501 created "2019-10-03" @default.
• W2975173501 creator A5036171723 @default.
• W2975173501 creator A5080055220 @default.
• W2975173501 date "2012-12-01" @default.
• W2975173501 modified "2023-09-23" @default.
• W2975173501 title "Impact of Atrial Fibrillation On Cardiovascular Mortality in the Setting of Myocardial Infarction." @default.
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• W2975173501 doi "https://doi.org/10.4022/jafib.722" @default.
• W2975173501 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5153162" @default.
• W2975173501 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28496798" @default.
• W2975173501 hasPublicationYear "2012" @default.
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