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- W2975599967 abstract "Traits of metabolic syndrome (MetS) and biomarkers of inflammation and endothelial dysfunction were examined. We investigated the differences of various biomarkers among individuals with or without Mets in a gender-specific manner. The gender-specific associations between E-selectin and MetS were further evaluated.A total of 205 patients were recruited from the outpatient clinics of Tri-Service General Hospital, Taipei, Taiwan. Inclusion criteria were age between 20-75 years and BMI < 35 kg/m2. Demographic, anthropometric and MetS index data were compared between genders. Markers of inflammation and endothelial dysfunction were compared between individuals with or without MetS by gender.Age-adjusted E-selectin values showed significant positive correlations with BMI, waist-hip ratio, fasting plasma glucose, systolic and diastolic blood pressure, triglycerides, TNF-α, hsCRP and ICAM-1, and inverse correlation with HDL cholesterol. E-selectin levels were positively correlated with numbers of MetS components in females (P < 0.001) but not in males (P = 0.125).Increased E-selectin levels are significantly associated with increased MetS risk in females, but not in males." @default.
- W2975599967 created "2019-10-03" @default.
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- W2975599967 date "2019-09-24" @default.
- W2975599967 modified "2023-10-15" @default.
- W2975599967 title "Serum E-selectin concentration is associated with risk of metabolic syndrome in females" @default.
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- W2975599967 doi "https://doi.org/10.1371/journal.pone.0222815" @default.
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