Matches in SemOpenAlex for { <https://semopenalex.org/work/W2976058326> ?p ?o ?g. }
- W2976058326 endingPage "127100" @default.
- W2976058326 startingPage "127100" @default.
- W2976058326 abstract "[Co(L)(H2O)2]ClO4 (where L denotes N,N′-Bis(3-methoxysalicylidene)-1,2-diaminopropane) was prepared, and its characterization was reported by single crystal X-ray crystallography, elemental analysis, mass spectrometry and spectroscopic methods (1H NMR, IR, and UV–Vis). The crystal structure showed that the arrangement around cobalt atom is octahedral with two imine nitrogen atoms (N1, N2) and two oxygen atoms of a hydroxyl group (O2, O3) in equatorial positions and two water molecules at the axial positions. The hydrogen bonding interactions between a coordinated water molecule and phenoxo/methoxy oxygens result in supermolecular dimers. Interaction of the complex with FS-DNA and protein (BSA) was explored by absorption and fluorescence spectroscopy. Moreover, Cyclic voltammetry (CV), viscosity measurements, circular dichroism (CD) and agarose gel electrophoresis were applied to determine the binding affinity to DNA. According to Kb value (≈102), the complex is moderately bound to DNA. The complex interacts with BSA by both static and dynamic quenching. Results of molecular docking were used to obtain detailed binding information of the complex to DNA and BSA. Cytotoxic activity was performed by MTT assay. It was observed that the complex exhibited low toxicity against the MCF-7 and LNCaP cancer cells." @default.
- W2976058326 created "2019-10-03" @default.
- W2976058326 creator A5009409813 @default.
- W2976058326 creator A5017077331 @default.
- W2976058326 creator A5044286688 @default.
- W2976058326 creator A5056295158 @default.
- W2976058326 date "2020-01-01" @default.
- W2976058326 modified "2023-10-01" @default.
- W2976058326 title "Crystal structure of a supramolecular dimer of Co(III) complex and evaluation of the DNA /BSA interaction" @default.
- W2976058326 cites W148058654 @default.
- W2976058326 cites W1550268932 @default.
- W2976058326 cites W1630786301 @default.
- W2976058326 cites W1975112195 @default.
- W2976058326 cites W1975999412 @default.
- W2976058326 cites W1977492525 @default.
- W2976058326 cites W1979995608 @default.
- W2976058326 cites W1987790825 @default.
- W2976058326 cites W1991897025 @default.
- W2976058326 cites W1995712792 @default.
- W2976058326 cites W2000866464 @default.
- W2976058326 cites W2004925055 @default.
- W2976058326 cites W2011199556 @default.
- W2976058326 cites W2021018103 @default.
- W2976058326 cites W2028428055 @default.
- W2976058326 cites W2028618950 @default.
- W2976058326 cites W2028689547 @default.
- W2976058326 cites W2031426081 @default.
- W2976058326 cites W2035813444 @default.
- W2976058326 cites W2037285570 @default.
- W2976058326 cites W2038124483 @default.
- W2976058326 cites W2043855224 @default.
- W2976058326 cites W2049639703 @default.
- W2976058326 cites W2051456776 @default.
- W2976058326 cites W2062532800 @default.
- W2976058326 cites W2062642504 @default.
- W2976058326 cites W2065485865 @default.
- W2976058326 cites W2074550194 @default.
- W2976058326 cites W2075705506 @default.
- W2976058326 cites W2078077330 @default.
- W2976058326 cites W2086382728 @default.
- W2976058326 cites W2101237607 @default.
- W2976058326 cites W2105144984 @default.
- W2976058326 cites W2114918609 @default.
- W2976058326 cites W2139701117 @default.
- W2976058326 cites W2161877652 @default.
- W2976058326 cites W2164188896 @default.
- W2976058326 cites W2165528549 @default.
- W2976058326 cites W2236136189 @default.
- W2976058326 cites W2324613566 @default.
- W2976058326 cites W2327828477 @default.
- W2976058326 cites W2357978564 @default.
- W2976058326 cites W2606862731 @default.
- W2976058326 cites W2752970728 @default.
- W2976058326 cites W2780241414 @default.
- W2976058326 cites W2790212269 @default.
- W2976058326 cites W2795333077 @default.
- W2976058326 cites W2888454143 @default.
- W2976058326 cites W2905555534 @default.
- W2976058326 cites W2917129753 @default.
- W2976058326 doi "https://doi.org/10.1016/j.molstruc.2019.127100" @default.
- W2976058326 hasPublicationYear "2020" @default.
- W2976058326 type Work @default.
- W2976058326 sameAs 2976058326 @default.
- W2976058326 citedByCount "6" @default.
- W2976058326 countsByYear W29760583262020 @default.
- W2976058326 countsByYear W29760583262021 @default.
- W2976058326 countsByYear W29760583262022 @default.
- W2976058326 countsByYear W29760583262023 @default.
- W2976058326 crossrefType "journal-article" @default.
- W2976058326 hasAuthorship W2976058326A5009409813 @default.
- W2976058326 hasAuthorship W2976058326A5017077331 @default.
- W2976058326 hasAuthorship W2976058326A5044286688 @default.
- W2976058326 hasAuthorship W2976058326A5056295158 @default.
- W2976058326 hasConcept C112887158 @default.
- W2976058326 hasConcept C115624301 @default.
- W2976058326 hasConcept C133571119 @default.
- W2976058326 hasConcept C178790620 @default.
- W2976058326 hasConcept C185592680 @default.
- W2976058326 hasConcept C2778271344 @default.
- W2976058326 hasConcept C2779546866 @default.
- W2976058326 hasConcept C32909587 @default.
- W2976058326 hasConcept C552990157 @default.
- W2976058326 hasConcept C55493867 @default.
- W2976058326 hasConcept C71240020 @default.
- W2976058326 hasConcept C8010536 @default.
- W2976058326 hasConcept C93275456 @default.
- W2976058326 hasConceptScore W2976058326C112887158 @default.
- W2976058326 hasConceptScore W2976058326C115624301 @default.
- W2976058326 hasConceptScore W2976058326C133571119 @default.
- W2976058326 hasConceptScore W2976058326C178790620 @default.
- W2976058326 hasConceptScore W2976058326C185592680 @default.
- W2976058326 hasConceptScore W2976058326C2778271344 @default.
- W2976058326 hasConceptScore W2976058326C2779546866 @default.
- W2976058326 hasConceptScore W2976058326C32909587 @default.
- W2976058326 hasConceptScore W2976058326C552990157 @default.
- W2976058326 hasConceptScore W2976058326C55493867 @default.
- W2976058326 hasConceptScore W2976058326C71240020 @default.
- W2976058326 hasConceptScore W2976058326C8010536 @default.