FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2976604562> ?p ?o ?g. }

• W2976604562 endingPage "427" @default.
• W2976604562 startingPage "420" @default.
• W2976604562 abstract "Objective Massive weight loss leads to marked knee pain reduction in individuals with knee pain, but the reason for the reduction in pain is unknown. This study was undertaken to quantify the contribution of magnetic resonance imaging ( MRI )–evidenced changes in pain‐sensitive structures, bone marrow lesions ( BML s), and synovitis, and changes in pain sensitization or depressive symptoms, to knee pain improvement after substantial weight loss. Methods Morbidly obese patients with knee pain on most days were evaluated before bariatric surgery or medical weight management and at 1‐year follow‐up for BML s and synovitis seen on MRI , the pressure pain threshold ( PPT ) at the patella and the right wrist, depressive symptoms (using the Center for Epidemiologic Studies Depression scale [ CES ‐D]), and Western Ontario and McMaster Universities Osteoarthritis Index ( WOMAC ) pain survey. Natural‐effects models were used to quantify the extent that achieving a minimum clinically important difference ( MCID ) of ≥18% on the WOMAC pain scale could be mediated by weight loss–induced changes in BML s, synovitis, PPT , and depressive symptoms. Results Of 75 participants, 53.3% lost ≥20% of weight by 1 year. Of these, 75% attained the MCID for pain improvement, compared with 34.3% in those who had <20% weight loss. Mediation analyses suggested that, in those with at least 20% weight loss, the odds of pain improvement increased by 62%, 15%, and 22% through changes in patella PPT , wrist PPT , and CES ‐D, respectively, but pain improvement was not mediated by MRI changes in BML s or synovitis. Conclusion Weight loss–induced knee pain improvement is partially mediated by changes in pain sensitization and depressive symptoms but is independent of MRI changes in BML s and synovitis." @default.
• W2976604562 created "2019-10-03" @default.
• W2976604562 creator A5022112585 @default.
• W2976604562 creator A5023227957 @default.
• W2976604562 creator A5041197177 @default.
• W2976604562 creator A5046252909 @default.
• W2976604562 creator A5068225825 @default.
• W2976604562 creator A5069018938 @default.
• W2976604562 creator A5083489256 @default.
• W2976604562 date "2020-01-22" @default.
• W2976604562 modified "2023-10-15" @default.
• W2976604562 title "Mediating Role of Bone Marrow Lesions, Synovitis, Pain Sensitization, and Depressive Symptoms on Knee Pain Improvement Following Substantial Weight Loss" @default.
• W2976604562 cites W1854018954 @default.
• W2976604562 cites W1926610892 @default.
• W2976604562 cites W1951724000 @default.
• W2976604562 cites W1973285887 @default.
• W2976604562 cites W1974165120 @default.
• W2976604562 cites W1982917662 @default.
• W2976604562 cites W1983189077 @default.
• W2976604562 cites W1983674530 @default.
• W2976604562 cites W1986158451 @default.
• W2976604562 cites W1997140718 @default.
• W2976604562 cites W1997637714 @default.
• W2976604562 cites W2003905926 @default.
• W2976604562 cites W2004162430 @default.
• W2976604562 cites W2004213014 @default.
• W2976604562 cites W2025773047 @default.
• W2976604562 cites W2034201007 @default.
• W2976604562 cites W2042801714 @default.
• W2976604562 cites W2068485217 @default.
• W2976604562 cites W2078072184 @default.
• W2976604562 cites W2097250275 @default.
• W2976604562 cites W2101308485 @default.
• W2976604562 cites W2103603390 @default.
• W2976604562 cites W2108740605 @default.
• W2976604562 cites W2112275504 @default.
• W2976604562 cites W2112778345 @default.
• W2976604562 cites W2144200965 @default.
• W2976604562 cites W2167933345 @default.
• W2976604562 cites W2274722622 @default.
• W2976604562 cites W2293040502 @default.
• W2976604562 cites W2306305052 @default.
• W2976604562 cites W2328169532 @default.
• W2976604562 cites W2331682781 @default.
• W2976604562 cites W2367473578 @default.
• W2976604562 cites W2408017125 @default.
• W2976604562 cites W2591836500 @default.
• W2976604562 cites W2600525865 @default.
• W2976604562 cites W2768335405 @default.
• W2976604562 cites W2782595898 @default.
• W2976604562 cites W2791380993 @default.
• W2976604562 cites W2963887880 @default.
• W2976604562 doi "https://doi.org/10.1002/art.41125" @default.
• W2976604562 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7050338" @default.
• W2976604562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31562683" @default.
• W2976604562 hasPublicationYear "2020" @default.
• W2976604562 type Work @default.
• W2976604562 sameAs 2976604562 @default.
• W2976604562 citedByCount "9" @default.
• W2976604562 countsByYear W29766045622021 @default.
• W2976604562 countsByYear W29766045622022 @default.
• W2976604562 countsByYear W29766045622023 @default.
• W2976604562 crossrefType "journal-article" @default.
• W2976604562 hasAuthorship W2976604562A5022112585 @default.
• W2976604562 hasAuthorship W2976604562A5023227957 @default.
• W2976604562 hasAuthorship W2976604562A5041197177 @default.
• W2976604562 hasAuthorship W2976604562A5046252909 @default.
• W2976604562 hasAuthorship W2976604562A5068225825 @default.
• W2976604562 hasAuthorship W2976604562A5069018938 @default.
• W2976604562 hasAuthorship W2976604562A5083489256 @default.
• W2976604562 hasBestOaLocation W29766045622 @default.
• W2976604562 hasConcept C126322002 @default.
• W2976604562 hasConcept C126838900 @default.
• W2976604562 hasConcept C141071460 @default.
• W2976604562 hasConcept C142724271 @default.
• W2976604562 hasConcept C143409427 @default.
• W2976604562 hasConcept C1862650 @default.
• W2976604562 hasConcept C204787440 @default.
• W2976604562 hasConcept C2776164576 @default.
• W2976604562 hasConcept C2777077863 @default.
• W2976604562 hasConcept C2777831278 @default.
• W2976604562 hasConcept C2778216619 @default.
• W2976604562 hasConcept C2779244835 @default.
• W2976604562 hasConcept C2779279471 @default.
• W2976604562 hasConcept C2779286237 @default.
• W2976604562 hasConcept C2779554423 @default.
• W2976604562 hasConcept C2780368125 @default.
• W2976604562 hasConcept C511355011 @default.
• W2976604562 hasConcept C544821477 @default.
• W2976604562 hasConcept C71924100 @default.
• W2976604562 hasConceptScore W2976604562C126322002 @default.
• W2976604562 hasConceptScore W2976604562C126838900 @default.
• W2976604562 hasConceptScore W2976604562C141071460 @default.
• W2976604562 hasConceptScore W2976604562C142724271 @default.
• W2976604562 hasConceptScore W2976604562C143409427 @default.
• W2976604562 hasConceptScore W2976604562C1862650 @default.
• W2976604562 hasConceptScore W2976604562C204787440 @default.
• W2976604562 hasConceptScore W2976604562C2776164576 @default.

• next