Matches in SemOpenAlex for { <https://semopenalex.org/work/W2977408857> ?p ?o ?g. }
- W2977408857 endingPage "1646.e3" @default.
- W2977408857 startingPage "1634" @default.
- W2977408857 abstract "Sulfolobus turreted icosahedral virus (STIV) is a model archaeal virus and member of the PRD1-adenovirus lineage. Although STIV employs pyramidal lysis structures to exit the host, knowledge of the viral entry process is lacking. We therefore initiated studies on STIV attachment and entry. Negative stain and cryoelectron micrographs showed virion attachment to pili-like structures emanating from the Sulfolobus host. Tomographic reconstruction and sub-tomogram averaging revealed pili recognition by the STIV C381 turret protein. Specifically, the triple jelly roll structure of C381 determined by X-ray crystallography shows that pilus recognition is mediated by conserved surface residues in the second and third domains. In addition, the STIV petal protein (C557), when present, occludes the pili binding site, suggesting that it functions as a maturation protein. Combined, these results demonstrate a role for the namesake STIV turrets in initial cellular attachment and provide the first molecular model for viral attachment in the archaeal domain of life." @default.
- W2977408857 created "2019-10-10" @default.
- W2977408857 creator A5006725047 @default.
- W2977408857 creator A5020027624 @default.
- W2977408857 creator A5035670521 @default.
- W2977408857 creator A5051362535 @default.
- W2977408857 creator A5056721802 @default.
- W2977408857 creator A5082833998 @default.
- W2977408857 creator A5086769360 @default.
- W2977408857 date "2019-11-01" @default.
- W2977408857 modified "2023-10-02" @default.
- W2977408857 title "The Molecular Mechanism of Cellular Attachment for an Archaeal Virus" @default.
- W2977408857 cites W1536978670 @default.
- W2977408857 cites W1869148146 @default.
- W2977408857 cites W1966408497 @default.
- W2977408857 cites W1975060596 @default.
- W2977408857 cites W1977633444 @default.
- W2977408857 cites W1978148961 @default.
- W2977408857 cites W1979513602 @default.
- W2977408857 cites W1983436559 @default.
- W2977408857 cites W1984962510 @default.
- W2977408857 cites W1991310235 @default.
- W2977408857 cites W1993556890 @default.
- W2977408857 cites W1996039824 @default.
- W2977408857 cites W1996347709 @default.
- W2977408857 cites W1998536115 @default.
- W2977408857 cites W1999907982 @default.
- W2977408857 cites W2001735605 @default.
- W2977408857 cites W2005092172 @default.
- W2977408857 cites W2010632792 @default.
- W2977408857 cites W2019003810 @default.
- W2977408857 cites W2021580655 @default.
- W2977408857 cites W2023156325 @default.
- W2977408857 cites W2026298026 @default.
- W2977408857 cites W2028360015 @default.
- W2977408857 cites W2028605946 @default.
- W2977408857 cites W2029101220 @default.
- W2977408857 cites W2030517878 @default.
- W2977408857 cites W2032604387 @default.
- W2977408857 cites W2035503835 @default.
- W2977408857 cites W2038016401 @default.
- W2977408857 cites W2051745967 @default.
- W2977408857 cites W2051758487 @default.
- W2977408857 cites W2052483647 @default.
- W2977408857 cites W2057430468 @default.
- W2977408857 cites W2061086279 @default.
- W2977408857 cites W2065424348 @default.
- W2977408857 cites W2066831210 @default.
- W2977408857 cites W2067704599 @default.
- W2977408857 cites W2073992907 @default.
- W2977408857 cites W2074827415 @default.
- W2977408857 cites W2075522211 @default.
- W2977408857 cites W2083410704 @default.
- W2977408857 cites W2084733368 @default.
- W2977408857 cites W2087960949 @default.
- W2977408857 cites W2090502454 @default.
- W2977408857 cites W2092431381 @default.
- W2977408857 cites W2095202929 @default.
- W2977408857 cites W2096025413 @default.
- W2977408857 cites W2096341610 @default.
- W2977408857 cites W2101305223 @default.
- W2977408857 cites W2103560959 @default.
- W2977408857 cites W2105259511 @default.
- W2977408857 cites W2106329030 @default.
- W2977408857 cites W2111424239 @default.
- W2977408857 cites W2113403117 @default.
- W2977408857 cites W2116175479 @default.
- W2977408857 cites W2117783316 @default.
- W2977408857 cites W2119481297 @default.
- W2977408857 cites W2122339645 @default.
- W2977408857 cites W2122609005 @default.
- W2977408857 cites W2123326582 @default.
- W2977408857 cites W2124842174 @default.
- W2977408857 cites W2125233707 @default.
- W2977408857 cites W2126295686 @default.
- W2977408857 cites W2131145661 @default.
- W2977408857 cites W2132629607 @default.
- W2977408857 cites W2132926880 @default.
- W2977408857 cites W2134216529 @default.
- W2977408857 cites W2137015675 @default.
- W2977408857 cites W2139501677 @default.
- W2977408857 cites W2142161929 @default.
- W2977408857 cites W2142497040 @default.
- W2977408857 cites W2142678478 @default.
- W2977408857 cites W2144081223 @default.
- W2977408857 cites W2149902614 @default.
- W2977408857 cites W2150959949 @default.
- W2977408857 cites W2151328227 @default.
- W2977408857 cites W2153438089 @default.
- W2977408857 cites W2157083464 @default.
- W2977408857 cites W2158714788 @default.
- W2977408857 cites W2164010203 @default.
- W2977408857 cites W2171012839 @default.
- W2977408857 cites W2171522138 @default.
- W2977408857 cites W2180229411 @default.
- W2977408857 cites W2277263366 @default.
- W2977408857 cites W2277506270 @default.
- W2977408857 cites W2279691890 @default.