FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2977409384> ?p ?o ?g. }

• W2977409384 endingPage "81" @default.
• W2977409384 startingPage "75" @default.
• W2977409384 abstract "Introduction: Myelosuppresion is a common side effect of chemotherapy and granulocyte-colony stimulating factor (G-CSF) is often used to reduce the risk of neutropenic events. The purpose of this exploratory analysis was to investigate neutropenic complications in the phase III PANTHER trial of standard 3-weekly chemotherapy with 5-fluorouracil, epirubicin and cyclophosphamide plus docetaxel (FEC/D) versus bi-weekly tailored dose-dense EC/D adjuvant chemotherapy in breast cancer.Patients and methods: Febrile neutropenia, neutropenic infection and infection grade 3-4 according to CTC AE 3.0, were explored in relation to G-CSF use. Per cycle analysis was performed concerning dose reduction and dose delays in conjunction with G-CSF administration.Results: In the experimental group, 98.9% of patients received primary G-CSF support during EC and 97.4% during docetaxel, compared with 49.7% during FEC and 63.88% during docetaxel in the standard group. Overall, the use of G-CSF was associated with a lower risk for developing neutropenic events (OR 0.44, 95% CI 0.35-0.55, p < .001). Chemotherapy delays due to neutropenia and leukopenia were significantly decreased among patients that received G-CSF (OR 0.098, 95% CI 0.06-0.15 and OR 0.32, 95% CI 0.18-0.58, respectively).Discussion: In conclusion, G-CSF support reduces neutropenic events and permits increased relative dose intensity, which is essential for improved survival outcomes." @default.
• W2977409384 created "2019-10-10" @default.
• W2977409384 creator A5000708354 @default.
• W2977409384 creator A5001256203 @default.
• W2977409384 creator A5003405177 @default.
• W2977409384 creator A5009097210 @default.
• W2977409384 creator A5026436902 @default.
• W2977409384 creator A5039948885 @default.
• W2977409384 creator A5039994927 @default.
• W2977409384 creator A5042560676 @default.
• W2977409384 creator A5064558241 @default.
• W2977409384 creator A5071571360 @default.
• W2977409384 creator A5075557023 @default.
• W2977409384 creator A5081499022 @default.
• W2977409384 creator A5087559224 @default.
• W2977409384 date "2019-10-04" @default.
• W2977409384 modified "2023-10-03" @default.
• W2977409384 title "Neutropenic complications in the PANTHER phase III study of adjuvant tailored dose-dense chemotherapy in early breast cancer" @default.
• W2977409384 cites W1530919096 @default.
• W2977409384 cites W1701849548 @default.
• W2977409384 cites W1804059878 @default.
• W2977409384 cites W194795933 @default.
• W2977409384 cites W1973258451 @default.
• W2977409384 cites W1978831940 @default.
• W2977409384 cites W1990248717 @default.
• W2977409384 cites W2000792702 @default.
• W2977409384 cites W2004900903 @default.
• W2977409384 cites W2011699001 @default.
• W2977409384 cites W2024933507 @default.
• W2977409384 cites W2036067444 @default.
• W2977409384 cites W2048687800 @default.
• W2977409384 cites W2049892213 @default.
• W2977409384 cites W2072300193 @default.
• W2977409384 cites W2083336892 @default.
• W2977409384 cites W2084654918 @default.
• W2977409384 cites W2092641204 @default.
• W2977409384 cites W2110534467 @default.
• W2977409384 cites W2110631033 @default.
• W2977409384 cites W2120388840 @default.
• W2977409384 cites W2127232551 @default.
• W2977409384 cites W2131278861 @default.
• W2977409384 cites W2169403306 @default.
• W2977409384 cites W2215157211 @default.
• W2977409384 cites W2233226443 @default.
• W2977409384 cites W2341045926 @default.
• W2977409384 cites W2550262309 @default.
• W2977409384 cites W2775811779 @default.
• W2977409384 cites W2898085761 @default.
• W2977409384 cites W2913286462 @default.
• W2977409384 cites W3048696092 @default.
• W2977409384 doi "https://doi.org/10.1080/0284186x.2019.1670353" @default.
• W2977409384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31583943" @default.
• W2977409384 hasPublicationYear "2019" @default.
• W2977409384 type Work @default.
• W2977409384 sameAs 2977409384 @default.
• W2977409384 citedByCount "9" @default.
• W2977409384 countsByYear W29774093842020 @default.
• W2977409384 countsByYear W29774093842021 @default.
• W2977409384 countsByYear W29774093842023 @default.
• W2977409384 crossrefType "journal-article" @default.
• W2977409384 hasAuthorship W2977409384A5000708354 @default.
• W2977409384 hasAuthorship W2977409384A5001256203 @default.
• W2977409384 hasAuthorship W2977409384A5003405177 @default.
• W2977409384 hasAuthorship W2977409384A5009097210 @default.
• W2977409384 hasAuthorship W2977409384A5026436902 @default.
• W2977409384 hasAuthorship W2977409384A5039948885 @default.
• W2977409384 hasAuthorship W2977409384A5039994927 @default.
• W2977409384 hasAuthorship W2977409384A5042560676 @default.
• W2977409384 hasAuthorship W2977409384A5064558241 @default.
• W2977409384 hasAuthorship W2977409384A5071571360 @default.
• W2977409384 hasAuthorship W2977409384A5075557023 @default.
• W2977409384 hasAuthorship W2977409384A5081499022 @default.
• W2977409384 hasAuthorship W2977409384A5087559224 @default.
• W2977409384 hasBestOaLocation W29774093841 @default.
• W2977409384 hasConcept C121608353 @default.
• W2977409384 hasConcept C126322002 @default.
• W2977409384 hasConcept C141071460 @default.
• W2977409384 hasConcept C143998085 @default.
• W2977409384 hasConcept C2776694085 @default.
• W2977409384 hasConcept C2776755627 @default.
• W2977409384 hasConcept C2777063308 @default.
• W2977409384 hasConcept C2777767877 @default.
• W2977409384 hasConcept C2778850193 @default.
• W2977409384 hasConcept C2780835546 @default.
• W2977409384 hasConcept C2780873365 @default.
• W2977409384 hasConcept C2781190966 @default.
• W2977409384 hasConcept C530470458 @default.
• W2977409384 hasConcept C71924100 @default.
• W2977409384 hasConcept C90924648 @default.
• W2977409384 hasConceptScore W2977409384C121608353 @default.
• W2977409384 hasConceptScore W2977409384C126322002 @default.
• W2977409384 hasConceptScore W2977409384C141071460 @default.
• W2977409384 hasConceptScore W2977409384C143998085 @default.
• W2977409384 hasConceptScore W2977409384C2776694085 @default.
• W2977409384 hasConceptScore W2977409384C2776755627 @default.
• W2977409384 hasConceptScore W2977409384C2777063308 @default.
• W2977409384 hasConceptScore W2977409384C2777767877 @default.
• W2977409384 hasConceptScore W2977409384C2778850193 @default.

• next