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- W2977453535 abstract "Introduction: little is known about the prevalence and characteristics of pancreatic cystic lesions among patients with cirrhosis. Many cirrhotic patients undergo transplant evaluation and the presence of potential neoplastic lesions in the pancreas warrants further investigation and follow up. Methods: after obtaining IRB approval, we performed a Natural Language Processing search of high quality imaging studies (CT scan, MRI/MRCP and EUS) of patients with documented liver cirrhosis seen in our institution between January 2008 and December 2014. Keywords searched within reports were: cyst, cystic, pseudocyst, IPMN, mucinous and lesion within 20 word distance of the word “Pancreas”. Results: 2605 individual patients with cirrhosis were identified. The prevalence of any cystic lesion in the pancreas was 4.9% (95% CI: 3.8%-5.6). Mean age was 59 year. Cysts were classified as potential neoplastic (mainly mucinous) in 26.7% (95% CI: 19.8-35.1), indeterminate in 11% (95% CI: 6.6-17.8) and pseudocyst/ simple in 62.3 (95%CI: 53.5-70.8%). Cysts were multiple in 19.7% of patients. All potentially neoplastic cysts were considered “low risk” for progression with no worrisome features and consisted mainly of side branch intraductal papillary mucinous neoplasm (82.4%). None of the potentially neoplastic cysts was >30mm in maximum dimension compared to 60.8% of pseudocysts (p Conclusion: The prevalence of pancreatic cystic lesions in patients with cirrhosis is close to 5%. Cyst size and underlying cirrhosis etiology are associated with cyst type with larger cysts and alcoholic cirrhosis are less likely to be neoplastic. A substantial number of pancreatic cystic lesions in cirrhotic patients are potentially low risk neoplastic cysts with side branch IPMN constituting the majority of it." @default.
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- W2977453535 date "2015-10-01" @default.
- W2977453535 modified "2023-09-27" @default.
- W2977453535 title "Prevalence and Characteristics of Pancreatic Cystic Lesions in Patients With Cirrhosis" @default.
- W2977453535 doi "https://doi.org/10.14309/00000434-201510001-02171" @default.
- W2977453535 hasPublicationYear "2015" @default.
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