Matches in SemOpenAlex for { <https://semopenalex.org/work/W2977455319> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2977455319 endingPage "18" @default.
- W2977455319 startingPage "17" @default.
- W2977455319 abstract "Squamous cell carcinomas are malignant epithelial tumors frequently found in patients over 60-65 years old, with only 1-6% [2] of the cases being diagnosed in patients younger than 40 years. Rarely, it appears as a sign or complication of a genetic condition such as Rothmund-Thomson syndrome or poikiloderma congenitale, an autosomal recessive disorder due to mutations of RECQL4 helicase gene on 8q24 [2]. Furthermore, there are only 300 cases reported in the literature so far [3]. Beside skin tumors, this condition is characterized by redness and atrophy of the skin, small stature, sparse hair, teeth and nails abnormalities, osteopenia, osteoporosis or osteosarcomas [4, 5]. We report an interesting case of a 32 year old patient known with Rothmund-Thomas syndrome and multiple skin tumors excised over the past few years, which presented with two skin tumors on the cheek and on the nasal region, measuring 1 cm and 0,7 cm in diameter (Figure 1). Histologically, both tumors were composed of malignant and pleomorphic keratinocytes, with enlarged nuclei, evident nucleoli and numerous atypical mitosis (Figure 2,3) infiltrating the deeper portions of the dermis. One tumor also presented keratin formation, thus diagnosed as keratinized squamous cell carcinoma, while the other was non-keratinized squamous cell carcinoma (Figure 4,5)." @default.
- W2977455319 created "2019-10-10" @default.
- W2977455319 creator A5024403229 @default.
- W2977455319 creator A5052926136 @default.
- W2977455319 creator A5071900316 @default.
- W2977455319 date "2018-11-20" @default.
- W2977455319 modified "2023-09-26" @default.
- W2977455319 title "Squamous cell carcionomas in a 31 year old patient with Rothmund-Thomson syndrome" @default.
- W2977455319 doi "https://doi.org/10.33695/mid.v1i1.11" @default.
- W2977455319 hasPublicationYear "2018" @default.
- W2977455319 type Work @default.
- W2977455319 sameAs 2977455319 @default.
- W2977455319 citedByCount "0" @default.
- W2977455319 crossrefType "journal-article" @default.
- W2977455319 hasAuthorship W2977455319A5024403229 @default.
- W2977455319 hasAuthorship W2977455319A5052926136 @default.
- W2977455319 hasAuthorship W2977455319A5071900316 @default.
- W2977455319 hasBestOaLocation W29774553191 @default.
- W2977455319 hasConcept C104317684 @default.
- W2977455319 hasConcept C142724271 @default.
- W2977455319 hasConcept C16005928 @default.
- W2977455319 hasConcept C2776330896 @default.
- W2977455319 hasConcept C2777624698 @default.
- W2977455319 hasConcept C2778156654 @default.
- W2977455319 hasConcept C2778163040 @default.
- W2977455319 hasConcept C2779915019 @default.
- W2977455319 hasConcept C2780713498 @default.
- W2977455319 hasConcept C2910980626 @default.
- W2977455319 hasConcept C55493867 @default.
- W2977455319 hasConcept C71924100 @default.
- W2977455319 hasConcept C86803240 @default.
- W2977455319 hasConceptScore W2977455319C104317684 @default.
- W2977455319 hasConceptScore W2977455319C142724271 @default.
- W2977455319 hasConceptScore W2977455319C16005928 @default.
- W2977455319 hasConceptScore W2977455319C2776330896 @default.
- W2977455319 hasConceptScore W2977455319C2777624698 @default.
- W2977455319 hasConceptScore W2977455319C2778156654 @default.
- W2977455319 hasConceptScore W2977455319C2778163040 @default.
- W2977455319 hasConceptScore W2977455319C2779915019 @default.
- W2977455319 hasConceptScore W2977455319C2780713498 @default.
- W2977455319 hasConceptScore W2977455319C2910980626 @default.
- W2977455319 hasConceptScore W2977455319C55493867 @default.
- W2977455319 hasConceptScore W2977455319C71924100 @default.
- W2977455319 hasConceptScore W2977455319C86803240 @default.
- W2977455319 hasIssue "1" @default.
- W2977455319 hasLocation W29774553191 @default.
- W2977455319 hasOpenAccess W2977455319 @default.
- W2977455319 hasPrimaryLocation W29774553191 @default.
- W2977455319 hasRelatedWork W1571270667 @default.
- W2977455319 hasRelatedWork W1976749069 @default.
- W2977455319 hasRelatedWork W1985215899 @default.
- W2977455319 hasRelatedWork W2011262897 @default.
- W2977455319 hasRelatedWork W2040299418 @default.
- W2977455319 hasRelatedWork W2073164993 @default.
- W2977455319 hasRelatedWork W2075249851 @default.
- W2977455319 hasRelatedWork W2152206937 @default.
- W2977455319 hasRelatedWork W2157249841 @default.
- W2977455319 hasRelatedWork W2939180994 @default.
- W2977455319 hasVolume "1" @default.
- W2977455319 isParatext "false" @default.
- W2977455319 isRetracted "false" @default.
- W2977455319 magId "2977455319" @default.
- W2977455319 workType "article" @default.