Matches in SemOpenAlex for { <https://semopenalex.org/work/W2977457194> ?p ?o ?g. }
- W2977457194 endingPage "16" @default.
- W2977457194 startingPage "10" @default.
- W2977457194 abstract "The current study was designed to determine the effect of centrally chronic-administrated histamine and histaminergic receptors antagonist on the hypothalamic cyclooxygenase (COX) and lipoxygenase (LOX) enzymes amount. Studies were performed in male Sprague–Dawley rats. Histamine (100 nmol), histaminergic H1 receptor antagonist chlorpheniramine (100 nmol), histaminergic H2 receptor antagonist ranitidine (100 nmol) or histaminergic H3/H4 receptor antagonist thioperamide (100 nmol) was injected intracerebroventricularly for 7 days. Central chronic histamine treatment caused an increase in all three enzymes amount in the hypothalamus. Histaminergic receptors antagonist chronic-treatments with chlorpheniramine, ranitidine and thioperamide produced to decrease in hypothalamic COX-1 amount and to increase in hypothalamic COX-2 and LOX amounts. In conclusion, our findings show that the central histaminergic system has a potential for effect the central COX and LOX pathways. This could be interpreted that central histaminergic and central COX and LOX pathways have an interaction to regulate in many central nervous system functions." @default.
- W2977457194 created "2019-10-10" @default.
- W2977457194 creator A5002152560 @default.
- W2977457194 creator A5003474664 @default.
- W2977457194 creator A5042997533 @default.
- W2977457194 creator A5059546960 @default.
- W2977457194 creator A5067336101 @default.
- W2977457194 creator A5068492642 @default.
- W2977457194 creator A5079739869 @default.
- W2977457194 creator A5085478605 @default.
- W2977457194 date "2019-12-18" @default.
- W2977457194 modified "2023-10-17" @default.
- W2977457194 title "Effect of Long-Term Centrally Injected Histamine and Its Receptors Antagonist on The Hypothalamic Cyclooxygenase and Lipoxygenase Enzymes in Rats" @default.
- W2977457194 cites W1977819088 @default.
- W2977457194 cites W1979584696 @default.
- W2977457194 cites W1986331805 @default.
- W2977457194 cites W1986802681 @default.
- W2977457194 cites W1998635895 @default.
- W2977457194 cites W1999558341 @default.
- W2977457194 cites W200454284 @default.
- W2977457194 cites W2015056616 @default.
- W2977457194 cites W2015210497 @default.
- W2977457194 cites W2018625136 @default.
- W2977457194 cites W2020814029 @default.
- W2977457194 cites W2022099467 @default.
- W2977457194 cites W2022823395 @default.
- W2977457194 cites W2023317778 @default.
- W2977457194 cites W2028533213 @default.
- W2977457194 cites W2030327444 @default.
- W2977457194 cites W2036332128 @default.
- W2977457194 cites W2037880596 @default.
- W2977457194 cites W2040088545 @default.
- W2977457194 cites W2041155755 @default.
- W2977457194 cites W2043688691 @default.
- W2977457194 cites W2045814907 @default.
- W2977457194 cites W2058159881 @default.
- W2977457194 cites W2059967591 @default.
- W2977457194 cites W2062320582 @default.
- W2977457194 cites W2094605937 @default.
- W2977457194 cites W2111140103 @default.
- W2977457194 cites W2112800119 @default.
- W2977457194 cites W2114629294 @default.
- W2977457194 cites W2114808045 @default.
- W2977457194 cites W2122373956 @default.
- W2977457194 cites W2123035658 @default.
- W2977457194 cites W2127898639 @default.
- W2977457194 cites W2133436949 @default.
- W2977457194 cites W2156174515 @default.
- W2977457194 cites W2157453831 @default.
- W2977457194 cites W2167141626 @default.
- W2977457194 cites W2173425296 @default.
- W2977457194 cites W2226488179 @default.
- W2977457194 cites W2325716920 @default.
- W2977457194 cites W2436985093 @default.
- W2977457194 cites W2460823943 @default.
- W2977457194 cites W2556168164 @default.
- W2977457194 cites W2605556626 @default.
- W2977457194 cites W2887694434 @default.
- W2977457194 doi "https://doi.org/10.30782/jrvm.606895" @default.
- W2977457194 hasPublicationYear "2019" @default.
- W2977457194 type Work @default.
- W2977457194 sameAs 2977457194 @default.
- W2977457194 citedByCount "0" @default.
- W2977457194 crossrefType "journal-article" @default.
- W2977457194 hasAuthorship W2977457194A5002152560 @default.
- W2977457194 hasAuthorship W2977457194A5003474664 @default.
- W2977457194 hasAuthorship W2977457194A5042997533 @default.
- W2977457194 hasAuthorship W2977457194A5059546960 @default.
- W2977457194 hasAuthorship W2977457194A5067336101 @default.
- W2977457194 hasAuthorship W2977457194A5068492642 @default.
- W2977457194 hasAuthorship W2977457194A5079739869 @default.
- W2977457194 hasAuthorship W2977457194A5085478605 @default.
- W2977457194 hasBestOaLocation W29774571941 @default.
- W2977457194 hasConcept C1122143 @default.
- W2977457194 hasConcept C126322002 @default.
- W2977457194 hasConcept C134018914 @default.
- W2977457194 hasConcept C159545944 @default.
- W2977457194 hasConcept C170493617 @default.
- W2977457194 hasConcept C185592680 @default.
- W2977457194 hasConcept C2776885963 @default.
- W2977457194 hasConcept C2778122271 @default.
- W2977457194 hasConcept C2778501154 @default.
- W2977457194 hasConcept C2778997900 @default.
- W2977457194 hasConcept C63180777 @default.
- W2977457194 hasConcept C71924100 @default.
- W2977457194 hasConcept C98274493 @default.
- W2977457194 hasConceptScore W2977457194C1122143 @default.
- W2977457194 hasConceptScore W2977457194C126322002 @default.
- W2977457194 hasConceptScore W2977457194C134018914 @default.
- W2977457194 hasConceptScore W2977457194C159545944 @default.
- W2977457194 hasConceptScore W2977457194C170493617 @default.
- W2977457194 hasConceptScore W2977457194C185592680 @default.
- W2977457194 hasConceptScore W2977457194C2776885963 @default.
- W2977457194 hasConceptScore W2977457194C2778122271 @default.
- W2977457194 hasConceptScore W2977457194C2778501154 @default.
- W2977457194 hasConceptScore W2977457194C2778997900 @default.
- W2977457194 hasConceptScore W2977457194C63180777 @default.
- W2977457194 hasConceptScore W2977457194C71924100 @default.