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- W2977522012 abstract "In Mexico, mortality secondary to congenital heart defects (CHD) has increased by almost 25% in the last 15 years, which highlights the lack of timely prenatal and neonatal diagnosis in our country. We aimed to describe our experience with prenatal diagnosis of CHD in patients referred to our Fetal Cardiology Unit. Prospective cohort study of consecutive fetuses referred for advanced fetal echocardiography to our Fetal Cardiology Unit during a 3-year period (September 2015–September 2018). 809 fetuses were evaluated, with 1263 fetal advanced echocardiographies performed. Suspected cardiac abnormality was the most common indication for referral (62.2%). Only 7.3% of patients had known morbidities or risk factors for CHD. A total of 528 (65.3%) fetuses were found to have a cardiac defect: 40.7% were isolated CHD while 24.6% had associated anomalies. The most common defects found were ventricular septal defects (20.3%), followed by conotruncal defects (9.7%), hypoplastic left heart syndrome (9.3%), fetal arrhythmias (8.9%) and venous anomalies (8.7%). 14 patients were considered candidates for intervention and had fetal surgery performed: 9 aortic valvuloplasties, 3 pulmonary valvuloplasties and 2 laser ablations of fetal tumors. 31.6% presented abnormal genetic studies, the most frequent being Down syndrome (23/212, 10.8%), followed by DiGeorge syndrome (11/212, 5.2%). This is the first study to report prospectively on prenatally diagnosed CHD in Mexico in a specialised Fetal Cardiology Unit. Prenatal screening and diagnosis of CHD in Mexico is feasible, but efforts must be made to make screening available to the general population, in order to identify fetal CHD and offer advanced echocardiography, genetic studies, timely fetal cardiac intervention in selected cases, and delivery in tertiary centres, to improve overall survival. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
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- W2977522012 date "2019-09-30" @default.
- W2977522012 modified "2023-10-16" @default.
- W2977522012 title "EP11.04: Experience of the first Fetal Cardiology Unit in Mexico" @default.
- W2977522012 doi "https://doi.org/10.1002/uog.21325" @default.
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