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- W2977732151 abstract "Purpose: Functional Bowel Disorders, a collection of symptom complex with disabling clinical state without any organic etiology. Prevalence is global with increasing morbidity affecting Quality of Life Score and compromised daily life style. Anorectal dysfunction with dysmotility is a salient clinical manifestation. This study evaluates Anorectal physiology in FBD. Methods: One hundred (n=100) patients were recruited with Group A control (n=50) male:female (25:25), Group B ROME 3 proven IBS with B1 Diarrheal (n=15) male:female (6:9), B2 Mixed (n=17) male:female (7:10) and B3 Constipation (N=18) male:female (5:13). All underwent stool, lab, to exclude infection, systemic disorders, proctoscopy, pre and post anorectal manometry and anorectal electromyography (EMG). Exclusion: Diabetes mellitus, pregnancy, Thyroid dysfunction, drugs affecting GI motility, known GI or systemic dysmotility, pelvic floor dysfunction, anal fissure or rectal incompetence. Results: Also see Table. Group A, 4/50 (8%) high sphincter pressure, 48/50 (96%) normal compliance, RAIR normal. Group B1: 4/15 (26%) altered squeeze pressure, 14/15 (94%) normal compliance, 14/15 (94%) RAIR normal. Group B2: 4/14 (28%) altered maximum squeeze pressure, 15/17 (88%) normal compliance, 16/17 (94%) normal RAIR. Group B3: 9/18 (50%) elevated resting pressure, 6/18 (33%) altered compliance, 2/18 (11%) altered RAIR. All subjects had normal EMG.Table: [1728] ResultsConclusion: This study reveals altered anorectal dynamics in FBS constipation type. Detailed neuro-physiological study needs to validate." @default.
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- W2977732151 date "2012-10-01" @default.
- W2977732151 modified "2023-09-27" @default.
- W2977732151 title "AnoRectal Dysfunction (ARD) in Functional Bowel Disorders (FBD): A Systematic Bio Mechanical Evaluation: Clinical Pilot Study" @default.
- W2977732151 doi "https://doi.org/10.14309/00000434-201210001-01728" @default.
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