FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2977736520> ?p ?o ?g. }

• W2977736520 endingPage "S389" @default.
• W2977736520 startingPage "S388" @default.
• W2977736520 abstract "Purpose: BACKGROUND: There are no published data to support the ASGE recommendation to hold clopidogrel (CLP) 7–10 days before polypectomy (GIE'05). Cessation of CLP may result in life threatening ischemic events. At our institution CLP is not routinely held prior to colonoscopy. AIM: To assess post-polypectomy bleeding (PPB) rate, risk factors and outcome of PPB in patients on CLP. Methods: We retrospectively reviewed electronic medical/pharmacy records of all patients on CLP who underwent colonoscopy (2002–07). Demographic, clinical, lab, polyp data & polypectomy methods were recorded. Post-procedure phone calls/clinic notes up to 6 weeks were abstracted. Management & outcome of PPB was reviewed. Univariate analysis was used to compare patients who had polypectomy on uninterrupted CLP (Gp A, N = 145) with randomly selected patients not on CLP, who had polypectomy during same period (Gp B, N = 1172). Results: 222 patients had colonoscopy & 145/222 had polypectomy without interruption of CLP. ▪ CLP indications: CAD 68%, stroke 21%, PVD 7.5%, other 4.0%. ▪ Duration of CLP use: <3 m, 8.3%; 3–12 m, 22%; >12 m, 70%. ▪ Gp A: total polyps removed 383, mean polyp no.: 2.6/pt; polyp size: range <5 to 30 mm. 8.4% were ≥ 10 mm, 27.7% were 5 to 9 mm. ▪ Polpypectomy method: cold-snare 28.5%, hot-snare 51%, cold-biopsy 9.7%, hot-biopsy 5.5%, unknown 5.3%. ▪ There were no significant differences in polyp number or polypectomy method between Gps A & B. Mean age, sex, race, INR, platelets, CrCl, smoking, alcohol use, COPD & NSAID use were also comparable. Gp A had significantly more HTN (83 vs 65%), DM (39 vs 26%), CAD (81 vs 25%) & ASA use (53 vs 32%) than Gp B respectively (all P < 0.05). ▪ PPB & outcome: PPB was significantly higher in the CLP group (8/145) (Table 1). Endoclips were applied in 3 pts for immediate bleeding, with good hemostasis. Delayed PPB occurred in 5 (median 10 d); 3/5 with delayed PPB had significant bleeding requiring hospitalization & blood transfusion (pRBC mean 3.6 units). Two, required repeat colonoscopy with endoclip-placement in one. No surgical/angiographic intervention was required. Average hospital stay was 3.7 days. There was no mortality. All patients with PPB on CLP also used ASA/other NSAIDs. 1/77 patients on CLP (no polypectomy) reported trivial rectal bleed one day post colonoscopy. Multiple logistic regression identified polyp number (OR 1.3, CI 1.2–1.4) & combined use of CLP & ASA/NSAID (OR 5.6, CI 2.2–14) as significant independent variables associated with PPB (P < 0.001), but use of CLP alone was not a significant factor.Table 1: Postpolypectomy bleeding (PPB) with and without clopidogrel useConclusion: PPB rate is higher in patients on CLP. It is the concurrent use of CLP with ASA/NSAIDs and not CLP use alone that confers this increased risk. The overall outcome remains favorable." @default.
• W2977736520 created "2019-10-10" @default.
• W2977736520 creator A5009761930 @default.
• W2977736520 creator A5011731786 @default.
• W2977736520 creator A5014224572 @default.
• W2977736520 creator A5079652865 @default.
• W2977736520 creator A5080048402 @default.
• W2977736520 creator A5083055117 @default.
• W2977736520 date "2008-09-01" @default.
• W2977736520 modified "2023-09-23" @default.
• W2977736520 title "Outcome in Two Hundred and Twenty Two Patients Undergoing Colonoscopy/Polypectomy on Uninterrupted Clopidogrel Therapy" @default.
• W2977736520 doi "https://doi.org/10.14309/00000434-200809001-00991" @default.
• W2977736520 hasPublicationYear "2008" @default.
• W2977736520 type Work @default.
• W2977736520 sameAs 2977736520 @default.
• W2977736520 citedByCount "2" @default.
• W2977736520 countsByYear W29777365202013 @default.
• W2977736520 countsByYear W29777365202017 @default.
• W2977736520 crossrefType "journal-article" @default.
• W2977736520 hasAuthorship W2977736520A5009761930 @default.
• W2977736520 hasAuthorship W2977736520A5011731786 @default.
• W2977736520 hasAuthorship W2977736520A5014224572 @default.
• W2977736520 hasAuthorship W2977736520A5079652865 @default.
• W2977736520 hasAuthorship W2977736520A5080048402 @default.
• W2977736520 hasAuthorship W2977736520A5083055117 @default.
• W2977736520 hasConcept C121608353 @default.
• W2977736520 hasConcept C126322002 @default.
• W2977736520 hasConcept C127413603 @default.
• W2977736520 hasConcept C141071460 @default.
• W2977736520 hasConcept C195910791 @default.
• W2977736520 hasConcept C2777628954 @default.
• W2977736520 hasConcept C2777849778 @default.
• W2977736520 hasConcept C2778435480 @default.
• W2977736520 hasConcept C2778451229 @default.
• W2977736520 hasConcept C2780581329 @default.
• W2977736520 hasConcept C2780645631 @default.
• W2977736520 hasConcept C526805850 @default.
• W2977736520 hasConcept C71924100 @default.
• W2977736520 hasConcept C78519656 @default.
• W2977736520 hasConceptScore W2977736520C121608353 @default.
• W2977736520 hasConceptScore W2977736520C126322002 @default.
• W2977736520 hasConceptScore W2977736520C127413603 @default.
• W2977736520 hasConceptScore W2977736520C141071460 @default.
• W2977736520 hasConceptScore W2977736520C195910791 @default.
• W2977736520 hasConceptScore W2977736520C2777628954 @default.
• W2977736520 hasConceptScore W2977736520C2777849778 @default.
• W2977736520 hasConceptScore W2977736520C2778435480 @default.
• W2977736520 hasConceptScore W2977736520C2778451229 @default.
• W2977736520 hasConceptScore W2977736520C2780581329 @default.
• W2977736520 hasConceptScore W2977736520C2780645631 @default.
• W2977736520 hasConceptScore W2977736520C526805850 @default.
• W2977736520 hasConceptScore W2977736520C71924100 @default.
• W2977736520 hasConceptScore W2977736520C78519656 @default.
• W2977736520 hasLocation W29777365201 @default.
• W2977736520 hasOpenAccess W2977736520 @default.
• W2977736520 hasPrimaryLocation W29777365201 @default.
• W2977736520 hasRelatedWork W1584895772 @default.
• W2977736520 hasRelatedWork W1598611506 @default.
• W2977736520 hasRelatedWork W1993020077 @default.
• W2977736520 hasRelatedWork W1998196357 @default.
• W2977736520 hasRelatedWork W2011758782 @default.
• W2977736520 hasRelatedWork W2096582894 @default.
• W2977736520 hasRelatedWork W2133147248 @default.
• W2977736520 hasRelatedWork W2803932775 @default.
• W2977736520 hasRelatedWork W2972741173 @default.
• W2977736520 hasRelatedWork W95487621 @default.
• W2977736520 hasVolume "103" @default.
• W2977736520 isParatext "false" @default.
• W2977736520 isRetracted "false" @default.
• W2977736520 magId "2977736520" @default.
• W2977736520 workType "article" @default.