Matches in SemOpenAlex for { <https://semopenalex.org/work/W2977765488> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2977765488 endingPage "103" @default.
- W2977765488 startingPage "82" @default.
- W2977765488 abstract "In this chapter, the chemistry of selected vanadium compounds and their ability to inhibit phosphatases and exhibit insulin-mimetic activities will be described. First, chemical properties are presented for three target groups of vanadium compounds inducing insulin-mimetic responses. The simple vanadate salts represent the group of vanadium compounds most studied and exhibit the most complex chemistry. The chemistry of a new peroxovanadium(V) compound is presented and a corresponding, isoelectronic hydroxylamido vanadium(V) complex is characterized. The similarities and differences between peroxovanadium and hydroxylamido compounds are identified. Bis(2,4-pentanedionato-O,O')oxovanadium(IV) (VO(acac)2) derivatives undergo hydrolysis reactions in aqueous solution which must be unraveled in order to appropriately interpret biological studies. Second, the effect of coordination number of vanadium compounds on their potency as a transition state analog inhibitor for a phosphatase is described. The five-coordinate vanadium(V) dipicolinic acid complex is found to be a more potent inhibitor than the six-coordinate vanadium(IV) dipicolinic acid complex and the seven-coordinate peroxooxovanadium(V) dipicolinic acid complex because of the structural analogy with the transition state of phosphate ester hydrolysis. Third, the effects of four types of peroxovanadium(V) compounds in phosphatase, insulin receptor and glucose-uptake assays are determined. The results show that although a series of peroxo compounds have significantly higher activity than vanadate in cell culture assays, such large differences are no longer apparent in the rat epitochlearis muscle." @default.
- W2977765488 created "2019-10-10" @default.
- W2977765488 creator A5061131260 @default.
- W2977765488 date "1998-12-10" @default.
- W2977765488 modified "2023-09-24" @default.
- W2977765488 title "Peroxo, Hydroxylamido, and Acac Derived Vanadium Complexes: Chemistry, Biochemistry, and Insulin-Mimetic Action of Selected Vanadium Compounds" @default.
- W2977765488 doi "https://doi.org/10.1021/bk-1998-0711.ch006" @default.
- W2977765488 hasPublicationYear "1998" @default.
- W2977765488 type Work @default.
- W2977765488 sameAs 2977765488 @default.
- W2977765488 citedByCount "13" @default.
- W2977765488 countsByYear W29777654882014 @default.
- W2977765488 countsByYear W29777654882015 @default.
- W2977765488 countsByYear W29777654882017 @default.
- W2977765488 countsByYear W29777654882023 @default.
- W2977765488 crossrefType "book-chapter" @default.
- W2977765488 hasAuthorship W2977765488A5061131260 @default.
- W2977765488 hasConcept C155647269 @default.
- W2977765488 hasConcept C174618031 @default.
- W2977765488 hasConcept C178790620 @default.
- W2977765488 hasConcept C179104552 @default.
- W2977765488 hasConcept C184651966 @default.
- W2977765488 hasConcept C185592680 @default.
- W2977765488 hasConcept C2775855980 @default.
- W2977765488 hasConcept C2781116636 @default.
- W2977765488 hasConcept C504678139 @default.
- W2977765488 hasConcept C544153396 @default.
- W2977765488 hasConcept C55493867 @default.
- W2977765488 hasConcept C59822182 @default.
- W2977765488 hasConcept C68913812 @default.
- W2977765488 hasConcept C71240020 @default.
- W2977765488 hasConcept C86803240 @default.
- W2977765488 hasConcept C94412978 @default.
- W2977765488 hasConceptScore W2977765488C155647269 @default.
- W2977765488 hasConceptScore W2977765488C174618031 @default.
- W2977765488 hasConceptScore W2977765488C178790620 @default.
- W2977765488 hasConceptScore W2977765488C179104552 @default.
- W2977765488 hasConceptScore W2977765488C184651966 @default.
- W2977765488 hasConceptScore W2977765488C185592680 @default.
- W2977765488 hasConceptScore W2977765488C2775855980 @default.
- W2977765488 hasConceptScore W2977765488C2781116636 @default.
- W2977765488 hasConceptScore W2977765488C504678139 @default.
- W2977765488 hasConceptScore W2977765488C544153396 @default.
- W2977765488 hasConceptScore W2977765488C55493867 @default.
- W2977765488 hasConceptScore W2977765488C59822182 @default.
- W2977765488 hasConceptScore W2977765488C68913812 @default.
- W2977765488 hasConceptScore W2977765488C71240020 @default.
- W2977765488 hasConceptScore W2977765488C86803240 @default.
- W2977765488 hasConceptScore W2977765488C94412978 @default.
- W2977765488 hasLocation W29777654881 @default.
- W2977765488 hasOpenAccess W2977765488 @default.
- W2977765488 hasPrimaryLocation W29777654881 @default.
- W2977765488 hasRelatedWork W1971893904 @default.
- W2977765488 hasRelatedWork W1975190873 @default.
- W2977765488 hasRelatedWork W2004832763 @default.
- W2977765488 hasRelatedWork W2016297156 @default.
- W2977765488 hasRelatedWork W2018225712 @default.
- W2977765488 hasRelatedWork W2050461441 @default.
- W2977765488 hasRelatedWork W2952760794 @default.
- W2977765488 hasRelatedWork W2953332163 @default.
- W2977765488 hasRelatedWork W2977765488 @default.
- W2977765488 hasRelatedWork W3192434528 @default.
- W2977765488 isParatext "false" @default.
- W2977765488 isRetracted "false" @default.
- W2977765488 magId "2977765488" @default.
- W2977765488 workType "book-chapter" @default.