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- W2977792689 abstract "Objective To evaluate the biocompatibility of thermosensitive chitosan hydrogel with periodontal ligament cells. Methods The periodontal ligament cells(PDL cells) were inoculated into the chitosan hydrogel scaffold for 3D culture. MTT,flow cytometry,cell viability staining was performed to evaluate the biocompatibility of the PDL cells cultured in the 3D hydrogel scaffold. Results By adding β-glycerophosphate(β-GP) into chitosan solution,gelation of thermosensitive hydrogel can be obtained under 37℃ within 30 min. Chitosan hydrogel extractions didn't inhibit PDL cell proliferation,and could increase the percentage of S-phase cells. Cell viability staining demonstrated that most of the PDL cells could survive in the chitosan hydrogel scaffold. Conclusion The thermosensitive chitosan hydrogel has excellent biocompatibility,which may be a promising injectable material for periodontal ligament tissue engineering." @default.
- W2977792689 created "2019-10-10" @default.
- W2977792689 creator A5069972768 @default.
- W2977792689 date "2013-01-01" @default.
- W2977792689 modified "2023-09-26" @default.
- W2977792689 title "Biocompatibility of thermosensitive chitosan hydrogel with periodontal ligament cells" @default.
- W2977792689 hasPublicationYear "2013" @default.
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