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- W2977797351 abstract "The aim of our study was to evaluate subclinical signs of fetal cardiovascular remodelling in late onset SGA fetuses using two-dimensional speckle-tracking echocardiography (2D-STE). Prospective case-control study, including 154 late onset small-for-gestational-age (SGA) fetuses and 139 healthy fetuses (≥ 15 at each gestational week between 32 and 41) as controls. Pregnancies complicated by structural or chromosomal anomalies of the fetus as well as conditions with possible effect on fetal cardiovascular function were excluded. Good quality of 2D apical four-chamber views for 2D-STE analyses were achieved in 101 out of 139 control fetuses (73%) and in 117 out of 154 SGA fetuses (76%). Cine loops were stored and analysed offline with a commercial software using the original acoustic frame rate (AFR). One fetal heart cycle was identified and selected by anatomical M-Mode. 2D-STE analyses included longitudinal peak systolic strain (LPSS) as well as longitudinal strain rate (LSR) of the left (LV) and right (RV) ventricle. For final analysis, 117 late-onset SGA (mean GA: 35.7 ± 1.9 weeks) and 101 control fetuses (mean GA: 36.3 ± 2.5 weeks) were included. Mean AFR was 129 ± 20 frames per second (fps) in the group of late-onset SGA fetuses and 120 ± 19 fps in the control group. Relating to LPSS values, there was no significant difference between late-onset SGA and control fetuses for both ventricles (LV −20.3% ± 4.7% vs. −20.1% ± 6.0%; p = 0.776 and RV −16.7% ± 5.4% vs. −16.4% ± 5.8%; p = 0.693). Likewise, no significant difference between late-onset SGA and control fetuses was observed for LSR values of both ventricles (LV 1.30 ± 0.31 1/s vs. 1.29 ± 0.36 1/s; p = 0.765 and RV 1.08 ± 0.38 1/s vs. 1.14 ± 0.45 1/s; p = 0.281). Fetal LPSS and LSR values for both ventricles showed no significant difference between late-onset SGA and control fetuses. However, subgroup analysis of SGA with and without normal fetomaternal Doppler or extremely small birth weight is still pending." @default.
- W2977797351 created "2019-10-10" @default.
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- W2977797351 date "2019-09-30" @default.
- W2977797351 modified "2023-10-18" @default.
- W2977797351 title "OP10.07: Myocardial deformation analysis in late‐onset small‐for‐gestational‐age fetuses using two‐dimensional speckle‐tracking echocardiography" @default.
- W2977797351 doi "https://doi.org/10.1002/uog.20746" @default.
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