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• W2977919555 abstract "The performance of the forced oscillation technique (FOT) in the assessment of bronchial responsiveness on the methacholine challenge test was com- pared with that of forced expiratory volume in one second (FEV 1 ) in 119 active workers with normal baseline pulmonary function. Changes in resistance (∆R 0 %), frequency dependence of resistance (∆P) and res- onant frequency (∆F%) determined by the FOT were compared to the ∆FEV 1 %. Receiver operating characteristic (ROC) curves were established to determine val- ues of the changes in FOT parameters which corresponded to the best sensitivity and specificity for classifying the subjects as hyperresponsive or nonresponsive on the methacholine challenge test. Significant correlations were observed between ∆FEV 1 % and ∆R 0 %, ∆P and ∆F% respectively. The ROC curves showed the following cut-off values of FOT para- meters to be the best values for classifying the subjects according to the presence or absence of 20% fall in FEV 1 : a 65% increase in R 0 (sensitivity 75%; specificity: 76%); a decrease of 65×10-3 hPa·l-1·s2 in P (sensitivity 58%; specificity 83%); a 50% increase in F (sensitivity 75%; specificity 62%). Our results suggest that the FOT is a useful test for assessment of bron- chial hyperresponsiveness when compared to spirometry, and can be applied to epidemiological studies of a bronchial challenge test in normal active working populations." @default.
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• W2977919555 date "1994-01-01" @default.
• W2977919555 modified "2023-09-22" @default.
• W2977919555 title "Measurement o of b bronchial rresponsiveness b by fforced o oscillation technique iin o occupational e epidemiology" @default.
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