FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2977947251> ?p ?o ?g. }

• W2977947251 endingPage "S752" @default.
• W2977947251 startingPage "S752" @default.
• W2977947251 abstract "A 55-year-old man with alcoholic cirrhosis presents after being found unresponsive at home. On route to the hospital, he had multiple episodes of coffee ground emesis. On admission, he was hemodynamically unstable and remained unresponsive. He was intubated, given packed red blood cells, started on nexium, octreotide and norepinephrine drips, and admitted to the MICU. An upper endoscopy revealed diffuse necrotic appearing esophagus, with confluent dark black areas and intermittent pale mucosal patches throughout the entire esophagus, but sparing the gastroesophageal (GE) junction. Hematin with diffuse moderate inflammation was seen in the gastric fundus and duodenum. Esophageal biopsies showed extensive necrotic debris with inflammation and black pigment deposition along the surface, consistent with acute esophageal necrosis (AEN). CT abdomen/pelvis showed a new pancreatic body mass with diffuse lymphadenopathy and nodules in lung, liver and adrenals. Superclavicular lymph node biopsy was consistent with pancreatic adenocarcinoma. Following biopsy, he remained encephalopathic and in persistent hemorrhagic and cardiogenic shock. He was transitioned to comfort care and expired from multi-system organ failure. Acute esophageal necrosis, or “black esophagus,” is a rare disorder, with a prevalence of approximately 0.2 percent.1 The condition is described as diffuse, circumferential black mucosal discoloration predominantly affecting the distal third of the esophagus and sparing the GE junction. The etiology is multifactorial and includes ischemic injury, corrosive injury from gastric contents in the setting of impaired motility, and impaired mucosal barrier systems.2 The most common risk factors include underlying malignancy and alcoholic cirrhosis. 70% of cases present with hematemesis and melena. Esophageal biopsies, however, are necessary to differentiate AEN from other etiologies.2 Management is largely supportive, aimed at correcting coexisting clinical conditions, as well as bowel rest and intravenous acid suppression with proton pump inhibitors. Complications include strictures, superinfections and perforation. While AEN does have a high mortality rate of 32%, it is largely due to the underlying clinical disease.2 Overall, acute esophageal necrosis is a rare condition, which should be viewed as a poor prognostic factor.Figure 1" @default.
• W2977947251 created "2019-10-10" @default.
• W2977947251 creator A5035291666 @default.
• W2977947251 creator A5059607973 @default.
• W2977947251 creator A5064260885 @default.
• W2977947251 creator A5085963117 @default.
• W2977947251 date "2016-10-01" @default.
• W2977947251 modified "2023-09-26" @default.
• W2977947251 title "A Rare Case of Acute Esophageal Necrosis in a Patient with Alcoholic Cirrhosis" @default.
• W2977947251 doi "https://doi.org/10.14309/00000434-201610001-01604" @default.
• W2977947251 hasPublicationYear "2016" @default.
• W2977947251 type Work @default.
• W2977947251 sameAs 2977947251 @default.
• W2977947251 citedByCount "0" @default.
• W2977947251 crossrefType "journal-article" @default.
• W2977947251 hasAuthorship W2977947251A5035291666 @default.
• W2977947251 hasAuthorship W2977947251A5059607973 @default.
• W2977947251 hasAuthorship W2977947251A5064260885 @default.
• W2977947251 hasAuthorship W2977947251A5085963117 @default.
• W2977947251 hasConcept C126322002 @default.
• W2977947251 hasConcept C142724271 @default.
• W2977947251 hasConcept C2776809568 @default.
• W2977947251 hasConcept C2777214474 @default.
• W2977947251 hasConcept C2777819096 @default.
• W2977947251 hasConcept C71924100 @default.
• W2977947251 hasConcept C90924648 @default.
• W2977947251 hasConceptScore W2977947251C126322002 @default.
• W2977947251 hasConceptScore W2977947251C142724271 @default.
• W2977947251 hasConceptScore W2977947251C2776809568 @default.
• W2977947251 hasConceptScore W2977947251C2777214474 @default.
• W2977947251 hasConceptScore W2977947251C2777819096 @default.
• W2977947251 hasConceptScore W2977947251C71924100 @default.
• W2977947251 hasConceptScore W2977947251C90924648 @default.
• W2977947251 hasLocation W29779472511 @default.
• W2977947251 hasOpenAccess W2977947251 @default.
• W2977947251 hasPrimaryLocation W29779472511 @default.
• W2977947251 hasRelatedWork W2167193069 @default.
• W2977947251 hasRelatedWork W2348751732 @default.
• W2977947251 hasRelatedWork W2349805151 @default.
• W2977947251 hasRelatedWork W2364478893 @default.
• W2977947251 hasRelatedWork W2381699712 @default.
• W2977947251 hasRelatedWork W2385697996 @default.
• W2977947251 hasRelatedWork W2391160944 @default.
• W2977947251 hasRelatedWork W2956098966 @default.
• W2977947251 hasRelatedWork W4231683837 @default.
• W2977947251 hasRelatedWork W4249146795 @default.
• W2977947251 hasVolume "111" @default.
• W2977947251 isParatext "false" @default.
• W2977947251 isRetracted "false" @default.
• W2977947251 magId "2977947251" @default.
• W2977947251 workType "article" @default.