FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2977963173> ?p ?o ?g. }

• W2977963173 endingPage "S759" @default.
• W2977963173 startingPage "S759" @default.
• W2977963173 abstract "The patient is a 78 year old female who was born in Buenos Aires before moving to the United States 40 years before her initial visit. She presented with progressive dysphagia, heartburn and epigastric pain. She did not have any cardiac symptoms or constipation. An EGD was performed which showed no signs of esophageal dilation or retention. The LES was easily traversed. An esophageal manometry (EM) showed that the LES relaxed well with most swallows, but several simultaneous contractions were present alternating with normal peristaltic waves. She was treated with an anti-reflux program with transient improvement. A year later, her symptoms recurred with chest pain, dysphagia to solids and liquids, and regurgitation. A repeat EM revealed over 30% simultaneous contractions that alternated with normally conducted peristaltic waves but also a poorly relaxing LES. BOTOX injection was done with symptomatic improvement. A year later, her symptoms recurred. A repeat EM was performed using a high-resolution manometry system. Findings were those of EGJ outlet obstruction with a mean IRP of 23.8 mmHg. No peristalsis was present and there was evidence of pan esophageal pressurization, overall consistent with the diagnosis of Achalasia (type II) as per the Chicago classification. A trypanosome antibody IgG was noted to be abnormal at 15 units. To her knowledge she was never exposed to any known tropical diseases. She underwent a laparoscopic Heller myotomy. She had improved relaxation of her LES, however, had persistent simultaneous contractions of the esophageal body. Chagas disease is caused by infection with the protozoan parasite Trypanosoma cruzi. Chagasic esophagus is seen in patients with the chronic form of the disease. The diagnosis of Chagas esophagus requires at least 3 requirements: a compatible history and clinical presentation, radiological and manometric abnormalities and serology tests to detect IgG antibodies to T. cruzi. Many patients are asymptomatic but still exhibit manometric changes while those with manometric changes may be asymptomatic. Management focuses on symptom amelioration with endoscopic dilatation or surgical options, including Per Oral Endoscopic Myotomy (POEM), being considered on an individual basis. It is important to be cognizant that there is Chagasic esophagus in the United States and to consider this in certain populations presenting with achalasia and even non-classic motility disorders that may be progressive or intermittent.Figure 1Figure 2" @default.
• W2977963173 created "2019-10-10" @default.
• W2977963173 creator A5008621931 @default.
• W2977963173 creator A5057554747 @default.
• W2977963173 creator A5071275315 @default.
• W2977963173 creator A5090887663 @default.
• W2977963173 date "2016-10-01" @default.
• W2977963173 modified "2023-09-27" @default.
• W2977963173 title "Chagasic Esophagus: An Unusual Presentation of Late Onset Dysphagia" @default.
• W2977963173 doi "https://doi.org/10.14309/00000434-201610001-01616" @default.
• W2977963173 hasPublicationYear "2016" @default.
• W2977963173 type Work @default.
• W2977963173 sameAs 2977963173 @default.
• W2977963173 citedByCount "0" @default.
• W2977963173 crossrefType "journal-article" @default.
• W2977963173 hasAuthorship W2977963173A5008621931 @default.
• W2977963173 hasAuthorship W2977963173A5057554747 @default.
• W2977963173 hasAuthorship W2977963173A5071275315 @default.
• W2977963173 hasAuthorship W2977963173A5090887663 @default.
• W2977963173 hasConcept C112497637 @default.
• W2977963173 hasConcept C126322002 @default.
• W2977963173 hasConcept C141071460 @default.
• W2977963173 hasConcept C206813253 @default.
• W2977963173 hasConcept C2776462128 @default.
• W2977963173 hasConcept C2776928572 @default.
• W2977963173 hasConcept C2777819096 @default.
• W2977963173 hasConcept C2778704086 @default.
• W2977963173 hasConcept C2779134260 @default.
• W2977963173 hasConcept C2779958274 @default.
• W2977963173 hasConcept C2780596822 @default.
• W2977963173 hasConcept C2781168508 @default.
• W2977963173 hasConcept C43270747 @default.
• W2977963173 hasConcept C71924100 @default.
• W2977963173 hasConcept C90924648 @default.
• W2977963173 hasConceptScore W2977963173C112497637 @default.
• W2977963173 hasConceptScore W2977963173C126322002 @default.
• W2977963173 hasConceptScore W2977963173C141071460 @default.
• W2977963173 hasConceptScore W2977963173C206813253 @default.
• W2977963173 hasConceptScore W2977963173C2776462128 @default.
• W2977963173 hasConceptScore W2977963173C2776928572 @default.
• W2977963173 hasConceptScore W2977963173C2777819096 @default.
• W2977963173 hasConceptScore W2977963173C2778704086 @default.
• W2977963173 hasConceptScore W2977963173C2779134260 @default.
• W2977963173 hasConceptScore W2977963173C2779958274 @default.
• W2977963173 hasConceptScore W2977963173C2780596822 @default.
• W2977963173 hasConceptScore W2977963173C2781168508 @default.
• W2977963173 hasConceptScore W2977963173C43270747 @default.
• W2977963173 hasConceptScore W2977963173C71924100 @default.
• W2977963173 hasConceptScore W2977963173C90924648 @default.
• W2977963173 hasLocation W29779631731 @default.
• W2977963173 hasOpenAccess W2977963173 @default.
• W2977963173 hasPrimaryLocation W29779631731 @default.
• W2977963173 hasRelatedWork W105583048 @default.
• W2977963173 hasRelatedWork W2008505345 @default.
• W2977963173 hasRelatedWork W2034043406 @default.
• W2977963173 hasRelatedWork W2083165648 @default.
• W2977963173 hasRelatedWork W2414106284 @default.
• W2977963173 hasRelatedWork W2423233162 @default.
• W2977963173 hasRelatedWork W2761250415 @default.
• W2977963173 hasRelatedWork W288930777 @default.
• W2977963173 hasRelatedWork W4290129178 @default.
• W2977963173 hasRelatedWork W78183485 @default.
• W2977963173 hasVolume "111" @default.
• W2977963173 isParatext "false" @default.
• W2977963173 isRetracted "false" @default.
• W2977963173 magId "2977963173" @default.
• W2977963173 workType "article" @default.