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- W2978018341 abstract "Recurrent urinary tract infections (UTIs) occur in up to ten percent of women and are a significant source of patient morbidity and health care costs. A variety of cranberry products have been used for UTI prevention, but no previous studies have examined whether consumption of dried cranberries will decrease the incidence of UTIs in susceptible patients. We conducted a clinical trial in which 20 women with a history of recurrent UTIs consumed one serving of sweetened, dried cranberries daily for two weeks. Patients reported the dates of UTIs in the six-month periods pre-and post-treatment. The efficacy of dried cranberry consumption in reducing UTI occurrence was determined by comparing pre-and post-treatment infection rates. Of the 17 patients who completed the study, nine (53%) did not experience any UTIs within six months after treatment, and the UTI rate per six months decreased significantly from 2.8 to 1.2 (p=0.005). Kaplan-Meier analysis compared the incidence of UTIs in study patients to patients receiving placebo in a previous UTI vaccine trial. Women in the two trials had equivalent UTI histories. This analysis showed a significant reduction in the number of UTIs in the six months post-treatment (p=0.02). Based on these two clinical evaluations, there appears to be a beneficial effect to consuming dried cranberries in reducing recurrent UTIs in susceptible women. Supported by Ocean Spray Cranberries, Inc" @default.
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- W2978018341 date "2012-04-01" @default.
- W2978018341 modified "2023-09-26" @default.
- W2978018341 title "Clinical Trial of Dried Cranberry Consumption to Reduce Urinary Tract Infection Incidence in Susceptible Women" @default.
- W2978018341 doi "https://doi.org/10.1096/fasebj.26.1_supplement.lb326" @default.
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