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- W2978054512 abstract "Purpose: 71-year-old Hispanic female patient underwent screening colonoscopy with complaints of recent onset of constipation and weight loss. At the same time an upper endoscopy was done to evaluate for decreased appetite and early satiety. She had significant past medical history for recurrence of breast cancer with diffuse skeletal metastasis 2 years ago after a decade of cancer free period. Currently, she was receiving palliative chemotherapy. On examination, she appeared cachectic and pale. Laboratory examination disclosed normocytic anemia, with a Hb level of 10.5 g/dL (normal range for Hb in our institution is 11.5–15.5 g/dL). Colonoscopy revealed an irregular configuration of the mucosal surface, luminal narrowing, and poor distensibility in the mid-transverse colon (Fig. A). Multiple biopsies were obtained. Histopathologic examination of the biopsy specimen revealed colonic mucosa with metastatic adenocarcinoma, morphologically consistent with lobular carcinoma of breast (Fig. B). EGD revealed thickened gastric folds; multiple biopsies were obtained. Histopathologic examination of the gastric biopsy specimens also revealed metastatic adenocarcinoma from breast. Extrahepatic gastrointestinal metastasis from breast cancer is uncommon. Metastases to the stomach and small bowel from breast cancer are reported to be more frequent than colonic and rectal involvement. Two reviews dealing with metastatic breast cancer have reported the involvement of colon in about 4% of the patients. Lobular carcinoma is the most common histological type of breast cancer that metastasizes to the colon and rectum. It is important to realize that patients with known breast cancer, especially of the lobular type, with vague, nonspecific abdominal signs and symptoms, particularly of an obstructing nature should be endoscopically screened for gastrointestinal metastases." @default.
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- W2978054512 date "2008-09-01" @default.
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- W2978054512 title "A Rare Case of Breast Cancer Metastasis Presenting as Linitis Plastica of Stomach and Colon" @default.
- W2978054512 doi "https://doi.org/10.14309/00000434-200809001-00914" @default.
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