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- W2978072914 abstract "Purpose: Recent controlled trials have shown that BT is more effective than sham feedback or standard therapy or diazepam in the short term treatment of dyssynergia (Gastroenterology 2005; 128: A266; A269). But, there has been no controlled long term study. Our aim was to compare 1 year outcome of BT (manometric- assisted pelvic relaxation, coordination and simulated defecation training), with standard therapy (ST; diet, exercise, laxatives). Methods: 52 patients (f/m = 47/5) with dyssynergic defecation were randomized. Stool diaries, visual analog scales (VAS), colon transit, anorectal manometry&balloon expulsion tests were assessed before, after therapy&at 1 year. Results: Table = mean ± sem. Repeated-measures ANOVAs,*= Fisher's exact. Bold = p < 0.05 (Table). 44/52 patients completed 3 months treatment (end active); 21 randomized to BT, 23 to ST and 8 dropped out. Subsequently, in the BT group, 13/21 completed 1 year follow up and 7 declined. In the ST group, 7/23 completed 1 year, 6 failed treatment (1 had surgery &5 Biofeedback) but were included in ITT analysis&10 declined. Dyssynergia pattern normalized, defecation index increased, balloon expulsion and colonic transit improved and bowel satisfaction improved in the BT group but not in the ST group.Table: No Caption available.Conclusions: Anorectal and colonic function and bowel satisfaction improved significantly in patients receiving biofeedback and was maintained at one year. In contrast, 46% patients failed standard therapy and there was little change in bowel function. Biofeedback is more effective than standard therapy in the long term treatment of dyssynergia. Supported by NIH1RO1[DK57100–0141] and NIH [HD41248–03]." @default.
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- W2978072914 date "2005-09-01" @default.
- W2978072914 modified "2023-10-01" @default.
- W2978072914 title "Randomized Controlled Trial of Long Term Outcome of Biofeedback Therapy (BT) for Dyssynergic Defecation" @default.
- W2978072914 doi "https://doi.org/10.14309/00000434-200509001-00386" @default.
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