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- W2978086718 abstract "Pantothenate is a crucial precursor for the biosynthesis of coenzyme A(CoA) and acyl carrier protein(ACP).It takes part in metabolism of carbohydrate,fatty acid,protein and energy.It is also involved in the synthesis of steroid,melatonin,antibody and heme.The process of biosynthesis is catalyzed by ketopantoate hydroxymethyltransferase,ketopantoate reductase,L-aspartate-α-decarboxylase and pantothenate synthetase.Plants and low organisms can synthesize pantothenate by themselves,so these enzymes would be specifically selective and potential drug targets.This review describes the functions of pantothenate and the structures and characteristics of the four enzymes in detail,which are related to biosynthesis pathway of pantothenate in E.coli and Mycobacterium tuberculosis." @default.
- W2978086718 created "2019-10-10" @default.
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- W2978086718 date "2008-01-01" @default.
- W2978086718 modified "2023-09-24" @default.
- W2978086718 title "The functions and biosynthesis of pantothenate" @default.
- W2978086718 hasPublicationYear "2008" @default.
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