FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2978166295> ?p ?o ?g. }

• W2978166295 endingPage "77" @default.
• W2978166295 startingPage "64" @default.
• W2978166295 abstract "ObjectiveTo assess benefits and harms of cognitive-behavioral therapy (CBT) versus no intervention or versus other interventions for pediatric obsessive-compulsive disorder (OCD).MethodWe searched for randomized clinical trials of CBT for pediatric OCD. Primary outcomes were OCD severity, serious adverse events, and level of functioning. Secondary outcomes were quality of life and adverse events. Remission from OCD was included as an exploratory outcome. We assessed risk of bias and evaluated the certainty of the evidence with the Grading of Recommendations Assessment, Development and Evaluation (GRADE).ResultsNine trials (N = 645) were included comparing CBT with no intervention and 3 trials (N = 146) comparing CBT with selective serotonin reuptake inhibitors (SSRIs). Compared with no intervention, CBT decreased OCD severity (mean difference [MD] = −8.51, 95% CI = −10.84 to −6.18, p < .00001, low certainty), improved level of functioning (patient-rated: standardized MD [SMD] = −0.90, 95% CI = −1.19 to −0.62, p < .00001, very low certainty; parent-rated: SMD = −0.68, 95% CI = −1.12 to −0.23, p = .003, very low certainty), had similar proportions of participants with adverse events (risk ratio = 1.06, 95% CI = 0.93−1.22, p = .39, GRADE: low certainty), and was associated with reduced risk of still having OCD (risk ratio = 0.50, 95% CI = 0.37−0.67, p < .00001, very low certainty). We had insufficient data to assess the effect of CBT versus no intervention on serious adverse events and quality of life. Compared with SSRIs, CBT led to similar decreases in OCD severity (MD = −0.75, 95% CI = −3.79 to 2.29, p = .63, GRADE: very low certainty), and was associated with similar risk of still having OCD (risk ratio = 0.85, 95% CI = 0.66−1.09, p = .20, very low certainty). We had insufficient data to assess the effect of CBT versus SSRIs on serious adverse events, level of functioning, quality of life, and adverse events.ConclusionCBT may be more effective than no intervention and comparable to SSRIs for pediatric OCD, but we are very uncertain about the effect estimates. To assess benefits and harms of cognitive-behavioral therapy (CBT) versus no intervention or versus other interventions for pediatric obsessive-compulsive disorder (OCD). We searched for randomized clinical trials of CBT for pediatric OCD. Primary outcomes were OCD severity, serious adverse events, and level of functioning. Secondary outcomes were quality of life and adverse events. Remission from OCD was included as an exploratory outcome. We assessed risk of bias and evaluated the certainty of the evidence with the Grading of Recommendations Assessment, Development and Evaluation (GRADE). Nine trials (N = 645) were included comparing CBT with no intervention and 3 trials (N = 146) comparing CBT with selective serotonin reuptake inhibitors (SSRIs). Compared with no intervention, CBT decreased OCD severity (mean difference [MD] = −8.51, 95% CI = −10.84 to −6.18, p < .00001, low certainty), improved level of functioning (patient-rated: standardized MD [SMD] = −0.90, 95% CI = −1.19 to −0.62, p < .00001, very low certainty; parent-rated: SMD = −0.68, 95% CI = −1.12 to −0.23, p = .003, very low certainty), had similar proportions of participants with adverse events (risk ratio = 1.06, 95% CI = 0.93−1.22, p = .39, GRADE: low certainty), and was associated with reduced risk of still having OCD (risk ratio = 0.50, 95% CI = 0.37−0.67, p < .00001, very low certainty). We had insufficient data to assess the effect of CBT versus no intervention on serious adverse events and quality of life. Compared with SSRIs, CBT led to similar decreases in OCD severity (MD = −0.75, 95% CI = −3.79 to 2.29, p = .63, GRADE: very low certainty), and was associated with similar risk of still having OCD (risk ratio = 0.85, 95% CI = 0.66−1.09, p = .20, very low certainty). We had insufficient data to assess the effect of CBT versus SSRIs on serious adverse events, level of functioning, quality of life, and adverse events. CBT may be more effective than no intervention and comparable to SSRIs for pediatric OCD, but we are very uncertain about the effect estimates." @default.
• W2978166295 created "2019-10-10" @default.
• W2978166295 creator A5018294219 @default.
• W2978166295 creator A5018314396 @default.
• W2978166295 creator A5019275846 @default.
• W2978166295 creator A5024824441 @default.
• W2978166295 creator A5031198235 @default.
• W2978166295 creator A5045625558 @default.
• W2978166295 creator A5052713065 @default.
• W2978166295 creator A5057232499 @default.
• W2978166295 creator A5088932508 @default.
• W2978166295 date "2020-01-01" @default.
• W2978166295 modified "2023-10-16" @default.
• W2978166295 title "Systematic Review and Meta-Analysis: Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder in Children and Adolescents" @default.
• W2978166295 cites W1541501625 @default.
• W2978166295 cites W1696716861 @default.
• W2978166295 cites W1918307986 @default.
• W2978166295 cites W1963955901 @default.
• W2978166295 cites W1964502734 @default.
• W2978166295 cites W1964710593 @default.
• W2978166295 cites W1969298821 @default.
• W2978166295 cites W1969859774 @default.
• W2978166295 cites W1971441597 @default.
• W2978166295 cites W1979475756 @default.
• W2978166295 cites W1983755959 @default.
• W2978166295 cites W1984723981 @default.
• W2978166295 cites W1986813456 @default.
• W2978166295 cites W1988175676 @default.
• W2978166295 cites W2005501262 @default.
• W2978166295 cites W2011059767 @default.
• W2978166295 cites W2016291757 @default.
• W2978166295 cites W2022700079 @default.
• W2978166295 cites W2034718004 @default.
• W2978166295 cites W2049700186 @default.
• W2978166295 cites W2059049783 @default.
• W2978166295 cites W2081271683 @default.
• W2978166295 cites W2081841619 @default.
• W2978166295 cites W2086148792 @default.
• W2978166295 cites W2087515016 @default.
• W2978166295 cites W2105125840 @default.
• W2978166295 cites W2106889389 @default.
• W2978166295 cites W2107328434 @default.
• W2978166295 cites W2108696783 @default.
• W2978166295 cites W2120322860 @default.
• W2978166295 cites W2121070134 @default.
• W2978166295 cites W2122350405 @default.
• W2978166295 cites W2125435699 @default.
• W2978166295 cites W2126930838 @default.
• W2978166295 cites W2142917088 @default.
• W2978166295 cites W2160238882 @default.
• W2978166295 cites W2160795579 @default.
• W2978166295 cites W2161571081 @default.
• W2978166295 cites W2165193663 @default.
• W2978166295 cites W2168767441 @default.
• W2978166295 cites W2171811563 @default.
• W2978166295 cites W2198741522 @default.
• W2978166295 cites W2288941264 @default.
• W2978166295 cites W2306891185 @default.
• W2978166295 cites W2420109333 @default.
• W2978166295 cites W2461177968 @default.
• W2978166295 cites W2513375206 @default.
• W2978166295 cites W2538766504 @default.
• W2978166295 cites W2593363470 @default.
• W2978166295 cites W3197972117 @default.
• W2978166295 doi "https://doi.org/10.1016/j.jaac.2019.08.480" @default.
• W2978166295 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31589909" @default.
• W2978166295 hasPublicationYear "2020" @default.
• W2978166295 type Work @default.
• W2978166295 sameAs 2978166295 @default.
• W2978166295 citedByCount "39" @default.
• W2978166295 countsByYear W29781662952020 @default.
• W2978166295 countsByYear W29781662952021 @default.
• W2978166295 countsByYear W29781662952022 @default.
• W2978166295 countsByYear W29781662952023 @default.
• W2978166295 crossrefType "journal-article" @default.
• W2978166295 hasAuthorship W2978166295A5018294219 @default.
• W2978166295 hasAuthorship W2978166295A5018314396 @default.
• W2978166295 hasAuthorship W2978166295A5019275846 @default.
• W2978166295 hasAuthorship W2978166295A5024824441 @default.
• W2978166295 hasAuthorship W2978166295A5031198235 @default.
• W2978166295 hasAuthorship W2978166295A5045625558 @default.
• W2978166295 hasAuthorship W2978166295A5052713065 @default.
• W2978166295 hasAuthorship W2978166295A5057232499 @default.
• W2978166295 hasAuthorship W2978166295A5088932508 @default.
• W2978166295 hasBestOaLocation W29781662951 @default.
• W2978166295 hasConcept C118552586 @default.
• W2978166295 hasConcept C126322002 @default.
• W2978166295 hasConcept C15744967 @default.
• W2978166295 hasConcept C168563851 @default.
• W2978166295 hasConcept C197934379 @default.
• W2978166295 hasConcept C27415008 @default.
• W2978166295 hasConcept C2781265626 @default.
• W2978166295 hasConcept C28804328 @default.
• W2978166295 hasConcept C70410870 @default.
• W2978166295 hasConcept C71924100 @default.
• W2978166295 hasConcept C95190672 @default.
• W2978166295 hasConceptScore W2978166295C118552586 @default.
• W2978166295 hasConceptScore W2978166295C126322002 @default.

• next