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- W2978218747 abstract "Objective To investigate the correlation between cyclic variation of integrated backscatter (CVIB) and nitric oxide (NO), nitric oxide synthase (NOS), wall thickening (WT) in stunned myocardium, and to provide objective and supportive basis for accuracy and reliability of CVIB which is applyied in detecting viable myocardium clinically.Methods Myocardial stunning models of dogs were made. The dynamic changes of CVIB and WT before and after LAD occlusion 30 min,and at 5 min, 15 min,30 min after reperfusion were measured. NO and NOS in coronary sinus blood were examined at the corresponding examining time. The correlation between CVIB and WT, NO, NOS was analyzed.Results After LAD occlusion 30min, the variables were significantly decreased (P 0.000 1 ), and gradually recovered after reperfusion. The tendency of these variables was similar. After reperfusion 30 min, the values of NO and NOS were all returned to baseline, but CVIB and WT only reached to 60.91 %± 11.27 % and 54.54 %± 13.17 %of the baseline(P 0.000 1 ), respectively. The correlation between CVIB and WT, NO, NOS was better at the different examining time, and the correlation coefficients were 0.712 ～ 0.842 (P 0.05 ). Conclusions The relation between CVIB and WT, which reflects the regional ventricular systolic function, was closer.There is also a better correlation between CVIB and NO, NOS, which affect the systolic function of stunned myocardium. Consequently, CVIB is an accurate and reliable variable in detecting viable myocardium." @default.
- W2978218747 created "2019-10-10" @default.
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- W2978218747 date "2002-01-01" @default.
- W2978218747 modified "2023-09-25" @default.
- W2978218747 title "Experimental study on the relation between cyclic variation of integrated backscatter and nitric oxide and nitric oxide synthase in stunned myocardium" @default.
- W2978218747 hasPublicationYear "2002" @default.
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