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• W2978276324 abstract "Abstract Background The neural crest is a group of multipotent cells that give rise to a wide variety of cells, especially portion of the peripheral nervous system. Neural crest cells (NCCs) show evolutionary conserved fate restrictions based on their axial level of origin: cranial, vagal, trunk, and sacral. While much is known about these cells in mammals, birds, amphibians, and fish, relatively little is known in other types of amniotes such as snakes, lizards, and turtles. We attempt here to provide a more detailed description of the early phase of trunk neural crest cell (tNCC) development in turtle embryos. Results In this study, we show, for the first time, migrating tNCC in the pharyngula embryo of Trachemys scripta by vital‐labeling the NCC with DiI and through immunofluorescence. We found that (a) tNCC form a line along the sides of the trunk NT; (b) The presence of late migrating tNCC on the medial portion of the somite; (c) The presence of lateral mesodermal migrating tNCC in pharyngula embryos; (d) That turtle embryos have large/thick peripheral nerves. Conclusions The similarities and differences in tNCC migration and early PNS development that we observe across sauropsids (birds, snake, gecko, and turtle) suggests that these species evolved some distinct NCC pathways." @default.
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• W2978276324 date "2019-10-09" @default.
• W2978276324 modified "2023-09-27" @default.
• W2978276324 title "The development of the trunk neural crest in the turtle<i>Trachemys scripta</i>" @default.
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• W2978276324 doi "https://doi.org/10.1002/dvdy.119" @default.
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