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- W2978282241 abstract "The question of a role for the adrenal glands in the regulation of gastric secre tion was raised in the early 1950's with the widespread use of corticosteroids and reports of an increased incidence of peptic ulcer following the administration of these agents. This led to an investigation of the mechanism of ulcer formation and of the possible role of the adrenal cortex in the maintenance of gastric secretory function. A classical method used in endocrinology is the removal of the gland under study and observation of the effect so produced. Fol lowing this, replacement therapy is used to ascertain whether the normal state can be restored. However, the adrenal gland has such widespread actions in the organism involving many systems that it is difficult to know whether any eff ect on the stomach is direct or secondary to some other al tered mechanism. It is the purpose of this reviewer to ex amine critically the evidence relating the adrenal glands with gastric secretion. This can be considered under four headings." @default.
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- W2978282241 date "1967-01-01" @default.
- W2978282241 modified "2023-09-26" @default.
- W2978282241 title "ROLE OF ADRENOCORTICAL STEROIDS IN THE REGULATION OF" @default.
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