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- W2978337867 abstract "Purpose: Development of cutaneous metastases from colon cancer is rare, and usually occurs in the setting of diffusely-disseminated disease and carries an extremely poor prognosis. We present a case of a 36 year-old male with cutaneous lesions on the lower extremities as the first presentation of metastatic disease from a colonic adenocarcinoma. Case: A 36 year-old Hispanic male with a history of colonic adenocarcinoma of the sigmoid colon status-post left hemicolectomy, presented with complaints of a lower-extremity nodular rash for two weeks. He first noticed the rash on his thighs that appeared in small “crops”, but progressively spread below his knees covering his bilateral lower extremities. Physical examination was remarkable for numerous cutaneous nodules over his lower extremities that were indolent, non-blanching, and immobile; with normal appearance of the overlying skin (Figures 1, 2). Excisional biopsy of the rash revealed cutaneous metastases secondary to adenocarcinoma of the colon. Imaging studies of the thorax, abdomen and pelvis were negative for any metastatic disease. The patient refused adjuvant chemotherapy. Seven months later, he presented with progressive dyspnea and weight loss. Computed tomography of the chest revealed widespread metastatic disease and patient died two months after hospitalization. Discussion: The most common site of cutaneous metastases from colon cancer is on the abdomen, and occurrences in previous scars after tumor resection have been described. Cutaneous metastasis to the lower extremities is extremely rare. Occurrence of skin metastases from colonic adenocarcinoma yields a poor prognosis, and average survival is 3 months after diagnosis.Figure: No Caption available.Figure: No Caption available." @default.
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- W2978337867 date "2011-10-01" @default.
- W2978337867 modified "2023-10-14" @default.
- W2978337867 title "Cutaneous Metastasis to the Lower Extremities from Adenocarcinoma of the Colon" @default.
- W2978337867 doi "https://doi.org/10.14309/00000434-201110002-00926" @default.
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