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- W2978370516 abstract "Purpose: About 30% of polyps are missed during standard colonoscopy (SC), e.g., due to polyps hidden behind haustral folds. This work explores a novel device and technique for increasing polyp and adenoma detection rate during colonoscopy. It employs a unique balloon-colonoscope (NaviAidTM G-EYETM, Smart Medical Systems Ltd., Ra'anana, Israel), comprising a standard colonoscope having a reprocessable, permanently integrated balloon at its distal tip. The balloon-colonoscope does not require pre-procedure preparation, mounting, or use of any single-use accessory. Balloon pressure is controlled through a unique inflation system providing pre-determined, user-selectable, anchoring and intermediate (low) pressure levels. Aim is to demonstrate added detection of polyps and adenomas using the NaviAidTM G-EYETM colonoscope. Methods: This is a prospective multicenter, randomized, tandem study. Patients referred to colonoscopy for screening, surveillance, or diagnostic work-up, were randomized into two groups. Group A underwent SC followed by G-EYETM Colonoscopy (GEC); group B underwent GEC followed by SC. During the GEC, the endoscope is inserted with the balloon deflated till the cecum. Then, the balloon is inflated to intermediate (low) pressure and the balloon-colonoscope is withdrawn, thus straightening intestinal folds, smoothening colon topography, and improving colon visibility. All polyps detected were removed. Results: 112 consecutive patients were enrolled and randomized between groups A and B. In group A, GEC performed following SC yielded polyp and adenoma additional detection rates of 100% and 78%, respectively. In group B, SC performed following GEC reported 7% and 4.2% additional detection rates of polyps and adenomas, respectively (implying 7% and 4.2% respective polyp and adenoma miss-rate of the GEC balloon-colonoscopy; Table 1). Balloon-colonoscope's additional detection rate ratio (ADRR, the ratio between GEC 2nd pass additional detection and GEC first pass miss-rate), is 100/7=14.3 for polyps and 78/4.2=18.7 for adenomas. For comparison, adenoma ADRR in published tandem studies of rear-viewing optics is 1.5 for TER (Avantis Medical) and 8.9 for FUSE (EndoChoice). Average procedure time of SC and GEC was similar. No complications occurred.Table 1: Summary of Polyp and Adenoma DetectionConclusion: GEC using the balloon-colonoscope and withdrawal technique is safe, easy to use, exhibits substantial increase in polyp/adenoma detection rate, and presents significant reduction in miss-rate during colonoscopy." @default.
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- W2978370516 date "2013-10-01" @default.
- W2978370516 modified "2023-09-23" @default.
- W2978370516 title "A Novel Balloon-colonoscope for Increased Polyp/Adenoma Detection Rate: Results of a Randomized Tandem Study: ACG Colorectal Cancer Prevention Award" @default.
- W2978370516 doi "https://doi.org/10.14309/00000434-201310001-02084" @default.
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