FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2978415978> ?p ?o ?g. }

• W2978415978 endingPage "113000" @default.
• W2978415978 startingPage "113000" @default.
• W2978415978 abstract "There are multiple research works that establish a relationship between Single Nucleotide Polymorphisms (SNPs) and complex diseases. In many cases, these diseases are caused by the interaction of two or more SNPs (epistasis). Therefore, it is important to identify which SNPs lead to the emergence of diseases. However, this problem gets harder when the epistasis order and the number of SNPs in the dataset under study are increased. To tackle this problem, this work presents an implementation of a multi-objective optimization algorithm with a problem-aware offspring process. Furthermore, due to the large amount of data in the SNPs datasets, we have also parallelized this algorithm. We experimentally validate the quality of the proposal under epistasis sizes of 2, 5, and 8 loci, although the application is not limited to those values. Moreover, a thorough comparative study of biological performance with six state-of-the-art methods has been conducted, obtaining better results than all the other biological methods. Our results confirm that, using the proposed approach, large datasets with high-order epistasis sizes can be processed in reasonable time, obtaining solutions of good quality. According to the literature review performed until the acceptance of this article, there are no other authors’ works that can process epistasis sizes above 6 loci in large datasets." @default.
• W2978415978 created "2019-10-10" @default.
• W2978415978 creator A5009435283 @default.
• W2978415978 creator A5044896136 @default.
• W2978415978 creator A5049408851 @default.
• W2978415978 creator A5053656021 @default.
• W2978415978 date "2020-03-01" @default.
• W2978415978 modified "2023-10-18" @default.
• W2978415978 title "A multi-objective optimization procedure for solving the high-order epistasis detection problem" @default.
• W2978415978 cites W1822695366 @default.
• W2978415978 cites W1868492295 @default.
• W2978415978 cites W1971299565 @default.
• W2978415978 cites W1974510435 @default.
• W2978415978 cites W1979673950 @default.
• W2978415978 cites W1986235130 @default.
• W2978415978 cites W2013443536 @default.
• W2978415978 cites W2016092929 @default.
• W2978415978 cites W2022485595 @default.
• W2978415978 cites W2031648200 @default.
• W2978415978 cites W2041170649 @default.
• W2978415978 cites W2041282815 @default.
• W2978415978 cites W2046316315 @default.
• W2978415978 cites W2046636211 @default.
• W2978415978 cites W2058322567 @default.
• W2978415978 cites W2070644791 @default.
• W2978415978 cites W2073835783 @default.
• W2978415978 cites W2098907614 @default.
• W2978415978 cites W2120423544 @default.
• W2978415978 cites W2123202052 @default.
• W2978415978 cites W2126105956 @default.
• W2978415978 cites W2126964466 @default.
• W2978415978 cites W2127474646 @default.
• W2978415978 cites W2145022912 @default.
• W2978415978 cites W2189123969 @default.
• W2978415978 cites W2307163007 @default.
• W2978415978 cites W2461189691 @default.
• W2978415978 cites W2617064902 @default.
• W2978415978 cites W2617467681 @default.
• W2978415978 cites W2621428960 @default.
• W2978415978 cites W2779655343 @default.
• W2978415978 cites W2883559393 @default.
• W2978415978 cites W2916339070 @default.
• W2978415978 cites W2947030066 @default.
• W2978415978 cites W2949922395 @default.
• W2978415978 doi "https://doi.org/10.1016/j.eswa.2019.113000" @default.
• W2978415978 hasPublicationYear "2020" @default.
• W2978415978 type Work @default.
• W2978415978 sameAs 2978415978 @default.
• W2978415978 citedByCount "4" @default.
• W2978415978 countsByYear W29784159782020 @default.
• W2978415978 countsByYear W29784159782021 @default.
• W2978415978 countsByYear W29784159782022 @default.
• W2978415978 countsByYear W29784159782023 @default.
• W2978415978 crossrefType "journal-article" @default.
• W2978415978 hasAuthorship W2978415978A5009435283 @default.
• W2978415978 hasAuthorship W2978415978A5044896136 @default.
• W2978415978 hasAuthorship W2978415978A5049408851 @default.
• W2978415978 hasAuthorship W2978415978A5053656021 @default.
• W2978415978 hasConcept C104317684 @default.
• W2978415978 hasConcept C111472728 @default.
• W2978415978 hasConcept C111919701 @default.
• W2978415978 hasConcept C119857082 @default.
• W2978415978 hasConcept C124101348 @default.
• W2978415978 hasConcept C135763542 @default.
• W2978415978 hasConcept C138885662 @default.
• W2978415978 hasConcept C153209595 @default.
• W2978415978 hasConcept C154945302 @default.
• W2978415978 hasConcept C2779530757 @default.
• W2978415978 hasConcept C41008148 @default.
• W2978415978 hasConcept C54355233 @default.
• W2978415978 hasConcept C61727976 @default.
• W2978415978 hasConcept C86803240 @default.
• W2978415978 hasConcept C98045186 @default.
• W2978415978 hasConceptScore W2978415978C104317684 @default.
• W2978415978 hasConceptScore W2978415978C111472728 @default.
• W2978415978 hasConceptScore W2978415978C111919701 @default.
• W2978415978 hasConceptScore W2978415978C119857082 @default.
• W2978415978 hasConceptScore W2978415978C124101348 @default.
• W2978415978 hasConceptScore W2978415978C135763542 @default.
• W2978415978 hasConceptScore W2978415978C138885662 @default.
• W2978415978 hasConceptScore W2978415978C153209595 @default.
• W2978415978 hasConceptScore W2978415978C154945302 @default.
• W2978415978 hasConceptScore W2978415978C2779530757 @default.
• W2978415978 hasConceptScore W2978415978C41008148 @default.
• W2978415978 hasConceptScore W2978415978C54355233 @default.
• W2978415978 hasConceptScore W2978415978C61727976 @default.
• W2978415978 hasConceptScore W2978415978C86803240 @default.
• W2978415978 hasConceptScore W2978415978C98045186 @default.
• W2978415978 hasFunder F4320334779 @default.
• W2978415978 hasFunder F4320335322 @default.
• W2978415978 hasLocation W29784159781 @default.
• W2978415978 hasOpenAccess W2978415978 @default.
• W2978415978 hasPrimaryLocation W29784159781 @default.
• W2978415978 hasRelatedWork W2961085424 @default.
• W2978415978 hasRelatedWork W3046775127 @default.
• W2978415978 hasRelatedWork W3107474891 @default.
• W2978415978 hasRelatedWork W3209574120 @default.
• W2978415978 hasRelatedWork W4205958290 @default.

• next