FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2978559310> ?p ?o ?g. }

• W2978559310 endingPage "1987" @default.
• W2978559310 startingPage "1978" @default.
• W2978559310 abstract "Abstract Introduction Sexual dysfunction is one of the most frequently occurring side-effects of antipsychotic medication, impacting both quality of life and adherence to treatment. Despite this, limited evidence-based guidance on treatment options is available. Aim To synthesize and analyze the evidence on management of antipsychotic-related sexual dysfunction, specifically taking note of the more recently developed antipsychotics that have been incorporated in studies over the past decade. Methods EMBASE, Medline, and PsychINFO databases were searched using search terms related to sexual or erectile dysfunction, treatments, and antipsychotics. 2 reviewers independently assessed papers for the inclusion criteria for randomized controlled trials (RCTs) of treatments for antipsychotic-related sexual dysfunction, including adjunctive medications and a switch of antipsychotic. Studies were excluded if participants did not have recorded sexual dysfunction at baseline. Main Outcome Measure The primary outcome measure was any change in sexual function. Results 6 RCTs were identified, all of which investigated different interventions; hence, it was not possible to synthesize the data quantitatively. Results were overall limited by small sample size, brief treatment duration, and the potential for bias. 2 studies, one assessing adjunctive sildenafil and the other adjunctive aripiprazole, reported a reduction in antipsychotic-related sexual dysfunction. Clinical Implications Due to the lack of high-quality data, no clinical recommendations can be made. Strengths & Limitations A comprehensive search strategy was used with an extensive number of relevant search terms including “erectile dysfunction” and newer antipsychotics such as aripiprazole. In light of evidence that prolactin is not a reliable marker for sexual dysfunction, this review focused its inclusion criteria on participants presenting with sexual dysfunction rather than with hyperprolactinemia, which should give its recommendations more validity. However, only 6 RCTs were identified, and results were overall limited by small sample size, brief treatment duration, and the potential for bias. Conclusion Our findings highlight the paucity of high-quality research in this area, and conjecture that it may be difficult to recruit participants with antipsychotic-related sexual dysfunction. Future research may be necessary to unlock and address these difficulties. Furthermore, fully powered future studies should focus on the management of sexual dysfunction rather than the surrogate marker of hyperprolactinemia." @default.
• W2978559310 created "2019-10-10" @default.
• W2978559310 creator A5002749019 @default.
• W2978559310 creator A5010544048 @default.
• W2978559310 creator A5021792283 @default.
• W2978559310 creator A5031605164 @default.
• W2978559310 date "2019-10-01" @default.
• W2978559310 modified "2023-10-14" @default.
• W2978559310 title "Management of Antipsychotic-Related Sexual Dysfunction: Systematic Review" @default.
• W2978559310 cites W1968296639 @default.
• W2978559310 cites W1983133139 @default.
• W2978559310 cites W1983848149 @default.
• W2978559310 cites W1983864587 @default.
• W2978559310 cites W1986183056 @default.
• W2978559310 cites W1987902149 @default.
• W2978559310 cites W1988082497 @default.
• W2978559310 cites W1990190466 @default.
• W2978559310 cites W1993351378 @default.
• W2978559310 cites W1995734872 @default.
• W2978559310 cites W2005114503 @default.
• W2978559310 cites W2005144130 @default.
• W2978559310 cites W2008008152 @default.
• W2978559310 cites W2013827816 @default.
• W2978559310 cites W2017994688 @default.
• W2978559310 cites W2027895008 @default.
• W2978559310 cites W2033224815 @default.
• W2978559310 cites W2035819314 @default.
• W2978559310 cites W2037132263 @default.
• W2978559310 cites W2041350562 @default.
• W2978559310 cites W2048163367 @default.
• W2978559310 cites W2071033221 @default.
• W2978559310 cites W2071057975 @default.
• W2978559310 cites W2073639928 @default.
• W2978559310 cites W2080844998 @default.
• W2978559310 cites W2081752752 @default.
• W2978559310 cites W2085636772 @default.
• W2978559310 cites W2096402187 @default.
• W2978559310 cites W2104552266 @default.
• W2978559310 cites W2114383226 @default.
• W2978559310 cites W2140896762 @default.
• W2978559310 cites W2156098321 @default.
• W2978559310 cites W2164182651 @default.
• W2978559310 cites W2167427568 @default.
• W2978559310 cites W2172047405 @default.
• W2978559310 cites W2173862535 @default.
• W2978559310 cites W2212925668 @default.
• W2978559310 cites W2244689641 @default.
• W2978559310 cites W2321504330 @default.
• W2978559310 cites W2488553311 @default.
• W2978559310 cites W2529424793 @default.
• W2978559310 cites W2555582253 @default.
• W2978559310 cites W2592300534 @default.
• W2978559310 cites W2764241479 @default.
• W2978559310 cites W2768500454 @default.
• W2978559310 cites W2786165002 @default.
• W2978559310 cites W2808012268 @default.
• W2978559310 cites W2991792334 @default.
• W2978559310 doi "https://doi.org/10.1016/j.jsxm.2019.08.022" @default.
• W2978559310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31585803" @default.
• W2978559310 hasPublicationYear "2019" @default.
• W2978559310 type Work @default.
• W2978559310 sameAs 2978559310 @default.
• W2978559310 citedByCount "16" @default.
• W2978559310 countsByYear W29785593102020 @default.
• W2978559310 countsByYear W29785593102021 @default.
• W2978559310 countsByYear W29785593102022 @default.
• W2978559310 countsByYear W29785593102023 @default.
• W2978559310 crossrefType "journal-article" @default.
• W2978559310 hasAuthorship W2978559310A5002749019 @default.
• W2978559310 hasAuthorship W2978559310A5010544048 @default.
• W2978559310 hasAuthorship W2978559310A5021792283 @default.
• W2978559310 hasAuthorship W2978559310A5031605164 @default.
• W2978559310 hasConcept C118552586 @default.
• W2978559310 hasConcept C126322002 @default.
• W2978559310 hasConcept C159110408 @default.
• W2978559310 hasConcept C168563851 @default.
• W2978559310 hasConcept C2775871022 @default.
• W2978559310 hasConcept C2776412080 @default.
• W2978559310 hasConcept C2778093883 @default.
• W2978559310 hasConcept C2779929075 @default.
• W2978559310 hasConcept C2779951463 @default.
• W2978559310 hasConcept C2780211496 @default.
• W2978559310 hasConcept C2780494398 @default.
• W2978559310 hasConcept C3018162438 @default.
• W2978559310 hasConcept C70410870 @default.
• W2978559310 hasConcept C71924100 @default.
• W2978559310 hasConceptScore W2978559310C118552586 @default.
• W2978559310 hasConceptScore W2978559310C126322002 @default.
• W2978559310 hasConceptScore W2978559310C159110408 @default.
• W2978559310 hasConceptScore W2978559310C168563851 @default.
• W2978559310 hasConceptScore W2978559310C2775871022 @default.
• W2978559310 hasConceptScore W2978559310C2776412080 @default.
• W2978559310 hasConceptScore W2978559310C2778093883 @default.
• W2978559310 hasConceptScore W2978559310C2779929075 @default.
• W2978559310 hasConceptScore W2978559310C2779951463 @default.
• W2978559310 hasConceptScore W2978559310C2780211496 @default.
• W2978559310 hasConceptScore W2978559310C2780494398 @default.
• W2978559310 hasConceptScore W2978559310C3018162438 @default.

• next