FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2978645964> ?p ?o ?g. }

• W2978645964 endingPage "1772" @default.
• W2978645964 startingPage "1767" @default.
• W2978645964 abstract "Abstract Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy (TMA) characterized by the severe deficiency of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13) activity (< 10%). Rapid ADAMTS13 testing is crucial for an early diagnosis and optimal management of acute TTP. We evaluated the performance of the HemosIL AcuStar ADAMTS13 activity assay (Instrumentation Laboratory, Bedford, Massachusetts, United States), a fully automated chemiluminescent immunoassay with an analytical time of 33 minutes. A method comparison study was performed on 176 samples from 49 healthy donors and 127 TMA patients (109 TTP, 7 atypical hemolytic uremic syndrome, 11 other TMAs), comparing this new assay with an in-house FRETS-VWF73 assay and a commercial enzyme-linked immunosorbent assay (ELISA) (TECHNOZYM ADAMTS-13 Activity, Technoclone GmbH, Vienna, Austria). Agreement between methods was assessed with focus on ADAMTS13 activity less than 10%, the medical decision level relevant for TTP diagnosis. The HemosIL AcuStar ADAMTS13 Activity showed good correlation with both the FRETS-VWF73 (r = 0.96) and ELISA (r = 0.96) methods. Slope of the Passing–Bablok regression was 1.05 for FRETS-VWF73 and 1.02 for ELISA, and absolute bias at the medical decision level was +0.1 and +0.3%, respectively. The study also revealed high agreement with FRETS-VWF73 (kappa 0.97) and ELISA (kappa 0.98) methods in classifying TTP patients with a severe deficiency of ADAMTS13 activity. Because of its short turnaround time and full automation, the HemosIL AcuStar ADAMTS13 activity assay might become the assay of choice to rapidly test ADAMTS13 activity in plasma and thus establish the diagnosis of acute TTP in emergency settings." @default.
• W2978645964 created "2019-10-10" @default.
• W2978645964 creator A5015768057 @default.
• W2978645964 creator A5018456564 @default.
• W2978645964 creator A5042034318 @default.
• W2978645964 creator A5047898833 @default.
• W2978645964 creator A5051527815 @default.
• W2978645964 creator A5060334504 @default.
• W2978645964 creator A5061651325 @default.
• W2978645964 creator A5065652666 @default.
• W2978645964 creator A5068346697 @default.
• W2978645964 creator A5074372785 @default.
• W2978645964 creator A5084764728 @default.
• W2978645964 creator A5085751554 @default.
• W2978645964 creator A5089130953 @default.
• W2978645964 creator A5090878807 @default.
• W2978645964 date "2019-10-06" @default.
• W2978645964 modified "2023-10-03" @default.
• W2978645964 title "Evaluation of a New, Rapid, Fully Automated Assay for the Measurement of ADAMTS13 Activity" @default.
• W2978645964 cites W1902980377 @default.
• W2978645964 cites W2030337128 @default.
• W2978645964 cites W2067632290 @default.
• W2978645964 cites W2146917249 @default.
• W2978645964 cites W2557184605 @default.
• W2978645964 cites W2796128753 @default.
• W2978645964 cites W2910737538 @default.
• W2978645964 doi "https://doi.org/10.1055/s-0039-1696718" @default.
• W2978645964 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31587247" @default.
• W2978645964 hasPublicationYear "2019" @default.
• W2978645964 type Work @default.
• W2978645964 sameAs 2978645964 @default.
• W2978645964 citedByCount "34" @default.
• W2978645964 countsByYear W29786459642020 @default.
• W2978645964 countsByYear W29786459642021 @default.
• W2978645964 countsByYear W29786459642022 @default.
• W2978645964 countsByYear W29786459642023 @default.
• W2978645964 crossrefType "journal-article" @default.
• W2978645964 hasAuthorship W2978645964A5015768057 @default.
• W2978645964 hasAuthorship W2978645964A5018456564 @default.
• W2978645964 hasAuthorship W2978645964A5042034318 @default.
• W2978645964 hasAuthorship W2978645964A5047898833 @default.
• W2978645964 hasAuthorship W2978645964A5051527815 @default.
• W2978645964 hasAuthorship W2978645964A5060334504 @default.
• W2978645964 hasAuthorship W2978645964A5061651325 @default.
• W2978645964 hasAuthorship W2978645964A5065652666 @default.
• W2978645964 hasAuthorship W2978645964A5068346697 @default.
• W2978645964 hasAuthorship W2978645964A5074372785 @default.
• W2978645964 hasAuthorship W2978645964A5084764728 @default.
• W2978645964 hasAuthorship W2978645964A5085751554 @default.
• W2978645964 hasAuthorship W2978645964A5089130953 @default.
• W2978645964 hasAuthorship W2978645964A5090878807 @default.
• W2978645964 hasBestOaLocation W29786459641 @default.
• W2978645964 hasConcept C109523444 @default.
• W2978645964 hasConcept C126322002 @default.
• W2978645964 hasConcept C159654299 @default.
• W2978645964 hasConcept C167814343 @default.
• W2978645964 hasConcept C203014093 @default.
• W2978645964 hasConcept C2776224515 @default.
• W2978645964 hasConcept C2777878052 @default.
• W2978645964 hasConcept C2778585876 @default.
• W2978645964 hasConcept C2779134260 @default.
• W2978645964 hasConcept C2780420688 @default.
• W2978645964 hasConcept C2780921031 @default.
• W2978645964 hasConcept C2909597000 @default.
• W2978645964 hasConcept C55728118 @default.
• W2978645964 hasConcept C71924100 @default.
• W2978645964 hasConcept C89560881 @default.
• W2978645964 hasConceptScore W2978645964C109523444 @default.
• W2978645964 hasConceptScore W2978645964C126322002 @default.
• W2978645964 hasConceptScore W2978645964C159654299 @default.
• W2978645964 hasConceptScore W2978645964C167814343 @default.
• W2978645964 hasConceptScore W2978645964C203014093 @default.
• W2978645964 hasConceptScore W2978645964C2776224515 @default.
• W2978645964 hasConceptScore W2978645964C2777878052 @default.
• W2978645964 hasConceptScore W2978645964C2778585876 @default.
• W2978645964 hasConceptScore W2978645964C2779134260 @default.
• W2978645964 hasConceptScore W2978645964C2780420688 @default.
• W2978645964 hasConceptScore W2978645964C2780921031 @default.
• W2978645964 hasConceptScore W2978645964C2909597000 @default.
• W2978645964 hasConceptScore W2978645964C55728118 @default.
• W2978645964 hasConceptScore W2978645964C71924100 @default.
• W2978645964 hasConceptScore W2978645964C89560881 @default.
• W2978645964 hasIssue "11" @default.
• W2978645964 hasLocation W29786459641 @default.
• W2978645964 hasLocation W29786459642 @default.
• W2978645964 hasLocation W29786459643 @default.
• W2978645964 hasOpenAccess W2978645964 @default.
• W2978645964 hasPrimaryLocation W29786459641 @default.
• W2978645964 hasRelatedWork W1967194398 @default.
• W2978645964 hasRelatedWork W2039241798 @default.
• W2978645964 hasRelatedWork W2043229074 @default.
• W2978645964 hasRelatedWork W2131949107 @default.
• W2978645964 hasRelatedWork W2158730091 @default.
• W2978645964 hasRelatedWork W2569964912 @default.
• W2978645964 hasRelatedWork W2796128753 @default.
• W2978645964 hasRelatedWork W2897799986 @default.
• W2978645964 hasRelatedWork W3029498159 @default.
• W2978645964 hasRelatedWork W4387082949 @default.

• next