FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2978735504> ?p ?o ?g. }

• W2978735504 endingPage "S157" @default.
• W2978735504 startingPage "S156" @default.
• W2978735504 abstract "Purpose: Roux-en-Y Gastric Bypass (RYGB) is the most common and effective procedure performed in the US for surgical treatment of obesity. The likelihood of having non-alcoholic fatty liver disease (NAFLD) is directly proportional to body weight1. NAFLD is being increasingly recognized as a major cause of liver-related morbidity and mortality. Given the increasing prevalence of obesity in North America, NAFLD is an important public health problem. The aim of this study is to determine the incidence of NAFLD in patients who underwent RYGB and to determine the effect of RYGB in a subgroup with abnormal liver tests (which include AST, ALT, alkaline phosphatase and bilirubin). Methods: 400 consecutive patients who underwent RYBP were evaluated retrospectively. Only those who underwent random intra-operative liver biopsy were included. Patients with viral or autoimmune hepatitis, hemochromatosis or alcohol use (>20g/day) were excluded. Pathological analysis recorded the presence and degree of steatosis, portal and lobular inflammation, and ballooning. Preoperative and 6–8 month postoperative clinical and laboratory data was gathered which included age, BMI, AST, ALT, alkaline phosphatase (AP) and bilirubin. Paired t-test was used to compare these variables pre and post operatively. Results: 205 patients were included in the study. 86.3% were female. The mean age was 36.8 ± 10.1 years. The mean BMI was 48.7 ± 7.4 kg/m2. 90.7% had NAFLD as proven by liver biopsy. All the patients with normal liver biopsy had normal liver tests. 25.9% of patients with NAFLD had abnormal liver tests prior to RYGB. Of these patients with abnormal liver tests, 24.5% had abnormal AST, 38.9% had abnormal ALT, 71.7% had abnormal AP and 9.4% had abnormal bilirubin. There was significant improvement of ALT (p= <0.001), AP (p= <0.001) and bilirubin (p= 0.003) after adjusting for the decrease in BMI postoperatively. Conclusions: Our study reiterates that NAFLD is highly prevalent in morbidly obese patients. About one-fourth of morbidly obese patients have abnormal liver tests. Significant improvement of ALT, alkaline phosphatase and bilirubin was noted after bariatric surgery." @default.
• W2978735504 created "2019-10-10" @default.
• W2978735504 creator A5000986747 @default.
• W2978735504 creator A5001357248 @default.
• W2978735504 creator A5043673166 @default.
• W2978735504 creator A5055557991 @default.
• W2978735504 creator A5071675585 @default.
• W2978735504 creator A5073326715 @default.
• W2978735504 creator A5074996220 @default.
• W2978735504 date "2006-09-01" @default.
• W2978735504 modified "2023-10-16" @default.
• W2978735504 title "Effect of Roux-en-Y Gastric Bypass (RYGB) on Clinical and Laboratory Data in Morbidly Obese Patients" @default.
• W2978735504 doi "https://doi.org/10.14309/00000434-200609001-00339" @default.
• W2978735504 hasPublicationYear "2006" @default.
• W2978735504 type Work @default.
• W2978735504 sameAs 2978735504 @default.
• W2978735504 citedByCount "0" @default.
• W2978735504 crossrefType "journal-article" @default.
• W2978735504 hasAuthorship W2978735504A5000986747 @default.
• W2978735504 hasAuthorship W2978735504A5001357248 @default.
• W2978735504 hasAuthorship W2978735504A5043673166 @default.
• W2978735504 hasAuthorship W2978735504A5055557991 @default.
• W2978735504 hasAuthorship W2978735504A5071675585 @default.
• W2978735504 hasAuthorship W2978735504A5073326715 @default.
• W2978735504 hasAuthorship W2978735504A5074996220 @default.
• W2978735504 hasConcept C126322002 @default.
• W2978735504 hasConcept C141071460 @default.
• W2978735504 hasConcept C160160445 @default.
• W2978735504 hasConcept C181199279 @default.
• W2978735504 hasConcept C185592680 @default.
• W2978735504 hasConcept C2775934546 @default.
• W2978735504 hasConcept C2776175330 @default.
• W2978735504 hasConcept C2777766500 @default.
• W2978735504 hasConcept C2777969384 @default.
• W2978735504 hasConcept C2778772119 @default.
• W2978735504 hasConcept C2779134260 @default.
• W2978735504 hasConcept C2779478299 @default.
• W2978735504 hasConcept C2780221984 @default.
• W2978735504 hasConcept C55493867 @default.
• W2978735504 hasConcept C71924100 @default.
• W2978735504 hasConcept C90924648 @default.
• W2978735504 hasConceptScore W2978735504C126322002 @default.
• W2978735504 hasConceptScore W2978735504C141071460 @default.
• W2978735504 hasConceptScore W2978735504C160160445 @default.
• W2978735504 hasConceptScore W2978735504C181199279 @default.
• W2978735504 hasConceptScore W2978735504C185592680 @default.
• W2978735504 hasConceptScore W2978735504C2775934546 @default.
• W2978735504 hasConceptScore W2978735504C2776175330 @default.
• W2978735504 hasConceptScore W2978735504C2777766500 @default.
• W2978735504 hasConceptScore W2978735504C2777969384 @default.
• W2978735504 hasConceptScore W2978735504C2778772119 @default.
• W2978735504 hasConceptScore W2978735504C2779134260 @default.
• W2978735504 hasConceptScore W2978735504C2779478299 @default.
• W2978735504 hasConceptScore W2978735504C2780221984 @default.
• W2978735504 hasConceptScore W2978735504C55493867 @default.
• W2978735504 hasConceptScore W2978735504C71924100 @default.
• W2978735504 hasConceptScore W2978735504C90924648 @default.
• W2978735504 hasLocation W29787355041 @default.
• W2978735504 hasOpenAccess W2978735504 @default.
• W2978735504 hasPrimaryLocation W29787355041 @default.
• W2978735504 hasRelatedWork W1966559673 @default.
• W2978735504 hasRelatedWork W1984443354 @default.
• W2978735504 hasRelatedWork W2036698572 @default.
• W2978735504 hasRelatedWork W2086939368 @default.
• W2978735504 hasRelatedWork W2088798319 @default.
• W2978735504 hasRelatedWork W2273678168 @default.
• W2978735504 hasRelatedWork W2467642010 @default.
• W2978735504 hasRelatedWork W2789841804 @default.
• W2978735504 hasRelatedWork W2978032175 @default.
• W2978735504 hasRelatedWork W4221035504 @default.
• W2978735504 hasVolume "101" @default.
• W2978735504 isParatext "false" @default.
• W2978735504 isRetracted "false" @default.
• W2978735504 magId "2978735504" @default.
• W2978735504 workType "article" @default.