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• W2978814865 abstract "FigureIntroduction: The key stage of the endoscopic full-thickness resection (EFTR) procedure is the successful closure of the gastric wall defect and thereby avoid surgical intervention. This report presents a new method of closing large gastric defects left by EFTR, using LeClampTM endoloops and metallic clips by means of single-channel endoscope.Figure 1Table 1: Clinical and histopathologic features of gastric fundus GISTs originating from the muscularis propria layer treated by endoscopic full-thickness resection (EFTR)Methods: We retrospectively analyzed 68 patients who were treated at four institutes between April 2014 and February 2015 with gastric fundus gastrointestinal stromal tumors (GISTs) originating from the muscularis propria layer and who consequently underwent EFTR. The large gastric post-EFTR defects were completely closed with metallic clips and novel endoloops using single-channel endoscope, and all patients were discharged with subsequent endoscopic and clinical follow-up. Patient characteristics, tumor size, en bloc resection, closure operation time, and postoperative adverse events were evaluated. Results: EFTR was successfully performed in 68 patients (41 male [60%], 27 female [40%]; median age 61 years, range 38-73; median lesion size 2.8cm, range 2.0-4.5cm) and the en bloc resection rate was 100%. Completely closure of all the gastric post-EFTR defects was achieved. The median closure operation time was 13 minutes (range 9-21min). The mean maximum size of the lesions was 2.8cm (range 2.0-4.5cm). One Mallory-Weiss syndrome and one delayed bleeding were resolved with nonsurgical treatment. The wounds were healed in all cases 1 month after the procedure. No residual tumor or tumor recurrence was observed during the follow-up period. Conclusion: The novel endoloops which we used in this study have demonstrated certain advantages, as follows: (1) It can be performed using single-channel endoscope, and it is a good news for those endoscopy units without equipped the dual-channel endoscope. (2) It is not needed to be preloaded prior to insertion and during closure procedures the loop can be conveniently introduced with the hemostasis clip, and then closed by a removable hook from the delivery system. (3) The ring-pull at the tail end of loops is larger than that of Olympus, so that it can be conveniently connected with the hook of the delivery system and greatly reduce the procedure time. (4) The endoloop is not expensive (600 RMB per loop). In summary, the use of metallic clips and novel endoloops with single-channel endoscope is a relatively safe, easy, and feasible method for repairing large gastric post-EFTR defects." @default.
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• W2978814865 date "2015-10-01" @default.
• W2978814865 modified "2023-10-15" @default.
• W2978814865 title "Endoscopic Closure of Gastric Defects Resulting From Endoscopic Full-thickness Resection by Application of Novel Endoloops and Metallic Clips, Using Single-Channel Endoscope: A Multicenter Study" @default.
• W2978814865 doi "https://doi.org/10.14309/00000434-201510001-01600" @default.
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