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- W2978870816 abstract "Objective To investigate the effect of secondary prevention of small dose Rosuvastation Calcium in elderly patients with transient ischemic attack(TIA).Methods The level of blood lipid,high-sensitivity C-reactive protein(hs-CRP) and homocysteine(Hcy) and carotid artery plaque were detected in 103 elderly patients with TIA.Patients treated with Rosuvastatin calcium dose of 5 mg / d,and reexamined 30 d and 180 d after treatment.Patients were followed up for 6 months.Results Compared with pre-treatment,the level of total cholesterol(TC),trigalloyl glycerol(TG),low density lipoprotein cholesterol(LDL-C),apoprotein A(Apo A),apoprotein B(Apo B),hsCRP,Hcy in 30 d and 180 d after treatment were significantly decreased,and high density lipoprotein cholesterol(HDL-C) was increased(P 0.05-0.01).The rate of reaching standard of LDL-C 2.07 mmol/L was 23.4% in 30 d after treatment,and there was 40.2% in 180 d after treatment.The rate of reaching standard of LDL-C 40% was 30.8% in 30 d after treatment,and there was 64.2% in 180 d after treatment.Compared with pre-treatment,the intima-media thickness(IMT) in 30 d after treatment were significantly decreased(P 0.05),and the IMT,low-density and mixed-density plaque area were significantly reduced in 180 d after treatment(all P 0.01).Follow-up 6 months,the TIA recurrence rate was in 11 cases(10.7%),alanine transaminase(ALT) 1ULN was in 9 cases(8.7%),ALT 3 upper limit of normal(ULN) in 1 case(1.0%),aspartate transaminase(AST) 1ULN in 3 cases(7.8%),ALT 3ULN in 2 cases(1.9%).Conclusion Small dose Rosuvastation Calcium for the elderly TIA patient is safe and effective,and suitable for long-term adherence to evidence-based secondary prevention therapies in cerebral stroke." @default.
- W2978870816 created "2019-10-10" @default.
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- W2978870816 date "2013-01-01" @default.
- W2978870816 modified "2023-09-24" @default.
- W2978870816 title "Curative effect of secondary prevention of small dose Rosuvastation Calcium in elderly patients with transient ischemic attack" @default.
- W2978870816 hasPublicationYear "2013" @default.
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