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- W2978888913 abstract "Compare perinatal and neurological outcomes between a fetoscopic myelomeningocele single-layer closure (SLC) and a three-layer closure (3LC) technique. An exteriorised uterus fetoscopic SLC technique was the initial approach used in our centre, but due to a high rate of CSF leak at birth, a 3LC was developed. Retrospective case control study: 32 consecutive SLC controls were compared with 18 consecutive 3LC cases performed in the same centre. All patients satisfied MOMS trial surgical eligibility criteria and had similar clinical management protocols. All cases had an exteriorised uterus approach, using 2/3 ports and CO2 for uterine insufflation. SLC consisted of a unified skin and dural closure in a single layer; the 3LC comprised 3 distinct layers: dural patch, myofascial layer and skin closure. Perinatal outcomes were similar between both groups. SLC showed a higher rate of CSF leak (8/32 (25%) vs. 3LC (0/17 (0%);p = 0.02), lower rate of reversal of hind brain herniation (18/30 (60%) vs 14/15 (93%);p = 0.02), and higher rate of hydrocephalus based on MOMS trial criteria (23/31 (74%) vs 3/11 (27%);p < 0.01). In their first year of life 15/32 (47%) SLC vs. 3/13 (23%) 3LC cases were treated for hydrocephalus (p = 0.14). Compared to SLC, 3LC preserves the fetal and obstetric benefits of fetoscopic repair, and shows improved neonatal neurological outcomes. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
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- W2978888913 date "2019-09-30" @default.
- W2978888913 modified "2023-09-27" @default.
- W2978888913 title "OP17.06: Comparison of two fetoscopic open neural tube defect repairs: single‐layer versus three‐layer spinal closure" @default.
- W2978888913 doi "https://doi.org/10.1002/uog.20821" @default.
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