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- W2978907031 abstract "Introduction: Previous studies have focused on outcome of psychiatric patients with pre-transplant diagnosis of depression in orthotopic liver transplantation (OLT), but there is a dearth of data on the outcomes of patients with bipolar disorder. Specifically, questions remain regarding factors that may influence the rate of readmission following OLT. Aim: To identify factors that may influence readmission within 30 days post OLT in patients with bipolar disorder. Methods: A retrospective study was performed to include patients who had a diagnosis of bipolar disorder and underwent OLT. Data from the time interval of 01/2000 and 12/2015 was abstracted by retrospective chart review, including the patients' and donors' demographics and perioperative variables. With those factors as statistical matching indexes, the data of a paired control group was collected. The major endpoint is to calculate the 30 days readmission rate. Results: A total of 2812 patients underwent OLT at our transplant center between 01/2000 and 12/2015. Of those, 19 patients (52.9±11.5 years, 63.2% male) with a previous diagnosis of bipolar disorder were identified, and 19 patients (53.6 ±11.4 years, 63.2% male) were selected in paired cohort. Etiology of liver diseases in case group includes chronic hepatitis C infection (7 patients), hepatitis B infection (3 patients), non-alcoholic steatohepatitis (2 patients), cryptogenic cirrhosis (2 patients), and other causes. Of these 19 patients, 7 patients (37%) had hepatocellular carcinoma. In case group, 7 patients (37%) were readmitted within 30 days post-OLT, with 1 patient due to a psychological reason. Eight patients were readmitted in control group. In both groups, those patients who were readmitted have relatively higher MELD score at OLT and longer post-op ICU stay, but only statistically significant in control group. Case group had longer hospital mainly due to non-psychological complications in one patient.Figure 1Conclusion: Readmission due to psychiatric issues within 30 days following OLT was uncommon in recipients with bipolar disorder. There is no difference of post-op readmission rate between patient with or without diagnosis of bipolar disorder prior to transplant. Perioperative factors did not influence readmission or outcomes following OLT, and bipolar disorder may not be a hurdle to be considered for liver transplant. Further study with larger number of patients warranted." @default.
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- W2978907031 date "2016-10-01" @default.
- W2978907031 modified "2023-09-26" @default.
- W2978907031 title "Perioperative Factors Influencing Readmissions of Liver Transplant Recipients with Bipolar Disorder" @default.
- W2978907031 doi "https://doi.org/10.14309/00000434-201610001-00893" @default.
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