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- W2978958224 abstract "Objective To establish an HPLC method for the determination of valsartan and amlodipine in valsartanand amlodipine Tablets.Methods Waters symmetry C18(3.9 mm×150 mm,5 μm)was used.The mobile phase was composed of acetonitrile∶ methanol∶ triethylamine solution(adjusted with phosphoric acid to a pH of 4.3±0.1) 15∶ 35∶ 50.The flow rate was 1.0 ml·min-1 and detection wavelength 237 nm.The temperacture was 30℃.The sample solution concentrations were amlodipine 5 mg·L-1,valsartan 160 mg·L-1.Results Valsartan concentration achieved good linearity in the range of 128.32~192.48 mg·L-1,n =5,r=0.999 7,amLodipine in the range between 2.00 and 12.00 mg·L-1,n=5,r=0.999 3.The average recoveries of valsartan and amlodipine were 99.93%,99.85%,and RSD were 0.30% and 0.34%.Conclusion This assay is simple,rapid,sensitive,accurate and reliable." @default.
- W2978958224 created "2019-10-10" @default.
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- W2978958224 date "2012-01-01" @default.
- W2978958224 modified "2023-09-28" @default.
- W2978958224 title "Determination of valsartan and amlodipine in valsartan and amlodipine tablets by HPLC" @default.
- W2978958224 hasPublicationYear "2012" @default.
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