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- W2978959957 abstract "A 24 yo female, with a history of sexually acquired HIV on no medication, presented complaining of epigastric abdominal pain associated with nausea and non-bloody vomiting for 7 days. She reported watery, non-bloody diarrhea for 3 months with a 10 pound weight loss, but denied any fever, chills, or change in appetite. On exam, she was afebrile with generalized wasting. Laboratory studies revealed 12.9 mg/dl Hgb, with the base line Hgb of 12–13 mg/dl, WBC = 1.7 with 61.6% neutrophils, 18.8% lymphocytes and a low CD4 count (< 20). Stool work up was negative for ova and parasites x 3, including Cryptosporidium parvum, wright stain and stool cultures were negative for WBCs and bacteria. Upper endoscopy and colonoscopy were performed. The antral mucosa was markedly erythematous, edematous and the mucosal surface was markedly friable. Thickened gastric folds were seen. Biopsies were taken of these areas. The colonic mucosa appeared normal. Histopathologic examination of antral and duodenal mucosal biopsies showed chronic active gastritis with extensive cryptosporidiosis and H. pylori organisms. Biopsies from the colonic mucosa were positive for Cryptosporidium parvum as well. In view of these findings, therapy with Alinia 500 mg twice daily was started. After 2 weeks, clinical improvement was observed with reduction of both epigastric pain and diarrhea. Repeat endoscopy 8 weeks later showed normal gastric mucosa. No organisms were identified on repeat antral and duodenal biopsies. Cryptosporidium parvum is a common protozoal infection that has been recognized as a human pathogen since 1976. It causes self-limited diarrhea in immunocompetent hosts, but severe and prolonged diarrhea in immunocompromised individuals, particularly those with HIV infection. Cryptosporidium parvum has been detected with increasing frequency in the gastrointestinal tract but involvement of the stomach is rarely reported. This case report presents the clinical, pathologic and endoscopic features of Cryptosporidium associated erosive gastritis and highlights the importance of upper endoscopy and biopsy in diagnosis of this entity. [figure 1]Figure 1" @default.
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- W2978959957 date "2006-09-01" @default.
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- W2978959957 title "A Case Presentation of Gastric Cryptosporidiosis in an HIV Patient" @default.
- W2978959957 doi "https://doi.org/10.14309/00000434-200609001-00968" @default.
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