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• W2979000715 abstract "Summary Plants plasmodesmata (PD) are important structures for plant. The biogenesis of PD is an important and poorly understood process. Remorin is a highly conserved PD protein, but its contribution to the formation of PD is difficult to study because of the redundancy of remorin in plants and the importance of PD for plant cell survival. We found expression of remorin in animal cells mimics a functional PD-like structure by deforming the membranes into filamentous vesicles. After systematic verification and comparison studies, we found remorin converts the animal cell membrane into remorin filaments (RFs). Interestingly, these PD-like remorin filaments are similar to the migrasome, a kind of material transfer structure on the surface of animal cells, from multiple aspects. Our studies not only reveal the mechanism of PD biogenesis, but also explain the fundamental links of intercellular transport systems between plants and mammals. In addition, the unique character and effect of remorin indicate the potential biomedical applications." @default.
• W2979000715 created "2019-10-10" @default.
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• W2979000715 date "2019-10-02" @default.
• W2979000715 modified "2023-09-23" @default.
• W2979000715 title "Expressing remorin in animal cells forms filamentous structure unraveling the mechanism of plasmodesmata biogenesis" @default.
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