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- W2979037340 abstract "This study reports a new stability indicating HPLC method using Spursil C18 column as stationary phase, and mixture of 0.1 M Na2HPO4 and methanol (50:50 v/v) as mobile phase for the chromatographic determination of paracetamol and prochlorperazine in tablets and in bulk form. The linearity range is 250-750 μg/mL for paracetamol and 2.5-7.5 μg/mL for prochlorperazine. The limit of detection values are 2.650 μg/mL for paracetamol and 0.175 μg/mL for prochlorperazine. The minor values of the relative standard deviation (≤ 2.0 %) as well as good percent assay values (nearer to 100 %) confirm the high precision and accuracy of the present method. From the degradation study chromatograms found that there was no interference from degradants when paracetamol and prochlorperazine are quantified in tablets through the proposed method. A good agreement between results obtained and labeled claim for the determination of paracetamol and prochlorperazine in tablet samples demonstrates that the proposed method is appropriate to quantify paracetamol and prochlorperazine in tablet formulations." @default.
- W2979037340 created "2019-10-10" @default.
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- W2979037340 date "2019-09-29" @default.
- W2979037340 modified "2023-10-16" @default.
- W2979037340 title "Quantification of Prochlorperazine and Paracetamol Using High Performance Liquid Chromatography: Application to Tablets and Stability Studies" @default.
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- W2979037340 doi "https://doi.org/10.14233/ajchem.2019.22140" @default.
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