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• W2979187893 abstract "Owing to the increasing drug-resistance, antibiotics-free strategy is urgent for the therapy of bacterial infections. Herein, Cu2+ is introduced into the porphyrin ring of PCN 224, which enhances the photocatalytic property of MOFs. The doped Cu2+ could trap electrons, thus suppresses electron-hole recombination and accelerates the transfer of carriers under 660 nm light irradiation, thereby enhancing the yields of reactive oxygen species (ROS). Furthermore, the Cu-MOFs’ photothermal effect is strengthened due to the d–d transition. However, overdoping of Cu2+ weakens the photocatalytic and photothermal properties due to the trapping of more photo-electrons by Cu2+ and the decreased light absorption of porphyrin at 660 nm. Doping with 10% Cu2+ endows the MOFs with the best antibacterial efficacy of 99.71% against Staphylococcus aureus within 20 min because of the synergistic effects of ROS and heat. Furthermore, the in vivo results show that Cu2+-MOFs kill bacteria efficiently, thus accelerating wound healing." @default.
• W2979187893 created "2019-10-10" @default.
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• W2979187893 date "2020-02-01" @default.
• W2979187893 modified "2023-10-17" @default.
• W2979187893 title "Enhanced photocatalytic activity and photothermal effects of cu-doped metal-organic frameworks for rapid treatment of bacteria-infected wounds" @default.
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• W2979187893 doi "https://doi.org/10.1016/j.apcatb.2019.118248" @default.
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