FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2979218211> ?p ?o ?g. }

• W2979218211 endingPage "S794" @default.
• W2979218211 startingPage "S793" @default.
• W2979218211 abstract "Introduction: Patients with Crohn's disease (CD) are susceptible to post-surgical infections which are associated with multiple risk factors, including blood transfusion (BT). The association between BT and postoperative complications in CD has been controversial according to previous institution-based population studies. The aim of this study was to clarify the association between perioperative BT and infectious complications in the CD patients by using a large national database, ie. the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP). Methods: Patients with CD who underwent surgery between 2005 and 2013 were identified from the NSQIP. Variables were defined according to the NSQIP guidelines. The primary outcome was infectious complications, including superficial, deep and organ/space surgical site infection, wound dehiscence, urinary tract infection, pneumonia, systemic sepsis and septic shock. Multivariate analyses were performed to assess the risk factors for postoperative infections. Results: A total of 10,100 patients with CD were identified and 611(6.0%) of them had perioperative blood transfusion. Those who needed transfusion were relatively older, lighter and more functionally dependent. The American Society of Anesthesiology (ASA) physical status classification for transfusion patients were mostly above level 3. Consequently, these patients had a longer operation time and total hospital stay. All infection related adverse outcomes were noted to have a higher prevalence in blood transfusion patients. Multivariate analysis for the risk factors of infections showed that intra- or post- operative BT was an independent risk factor (with odds ratio [OR], 2.2; 95% confidence interval [CI],1.8-2.7; P < 0.0001)and risk increased with each increased unit of RBC (OR: 1.3, 95% CI: 1.2-1.5). Other possible risk factors were listed in Table 2. Preoperative BT, however, was not an independent contributor to postoperative infections.Table 2: Multivariate analysis of risk factors for post-operative infection complication in Crohn's diseaseConclusion:Intra-and post-operative, not preoperative, blood transfusion is associated with an increased risk for postoperative infectious complications in CD. Therefore, anemic patients may be transfused before surgery but the risks and benefits of transfusion of red blood cells, acting as an immunosuppressive agent, should still be carefully balanced in the current wide use of biological agents.Table 1: Demographic differences and post-operation complications between patients with and without transfusionTable 1: Continued" @default.
• W2979218211 created "2019-10-10" @default.
• W2979218211 creator A5010804802 @default.
• W2979218211 creator A5012906393 @default.
• W2979218211 creator A5015105154 @default.
• W2979218211 creator A5037330137 @default.
• W2979218211 creator A5055431287 @default.
• W2979218211 date "2015-10-01" @default.
• W2979218211 modified "2023-09-27" @default.
• W2979218211 title "Perioperative Blood Transfusion Is Associated With Postoperative Infection in Patients With Crohnʼs Disease" @default.
• W2979218211 doi "https://doi.org/10.14309/00000434-201510001-01866" @default.
• W2979218211 hasPublicationYear "2015" @default.
• W2979218211 type Work @default.
• W2979218211 sameAs 2979218211 @default.
• W2979218211 citedByCount "0" @default.
• W2979218211 crossrefType "journal-article" @default.
• W2979218211 hasAuthorship W2979218211A5010804802 @default.
• W2979218211 hasAuthorship W2979218211A5012906393 @default.
• W2979218211 hasAuthorship W2979218211A5015105154 @default.
• W2979218211 hasAuthorship W2979218211A5037330137 @default.
• W2979218211 hasAuthorship W2979218211A5055431287 @default.
• W2979218211 hasConcept C126322002 @default.
• W2979218211 hasConcept C141071460 @default.
• W2979218211 hasConcept C156957248 @default.
• W2979218211 hasConcept C2777628635 @default.
• W2979218211 hasConcept C2778384902 @default.
• W2979218211 hasConcept C2779526319 @default.
• W2979218211 hasConcept C2780014101 @default.
• W2979218211 hasConcept C31174226 @default.
• W2979218211 hasConcept C42219234 @default.
• W2979218211 hasConcept C50440223 @default.
• W2979218211 hasConcept C71924100 @default.
• W2979218211 hasConceptScore W2979218211C126322002 @default.
• W2979218211 hasConceptScore W2979218211C141071460 @default.
• W2979218211 hasConceptScore W2979218211C156957248 @default.
• W2979218211 hasConceptScore W2979218211C2777628635 @default.
• W2979218211 hasConceptScore W2979218211C2778384902 @default.
• W2979218211 hasConceptScore W2979218211C2779526319 @default.
• W2979218211 hasConceptScore W2979218211C2780014101 @default.
• W2979218211 hasConceptScore W2979218211C31174226 @default.
• W2979218211 hasConceptScore W2979218211C42219234 @default.
• W2979218211 hasConceptScore W2979218211C50440223 @default.
• W2979218211 hasConceptScore W2979218211C71924100 @default.
• W2979218211 hasLocation W29792182111 @default.
• W2979218211 hasOpenAccess W2979218211 @default.
• W2979218211 hasPrimaryLocation W29792182111 @default.
• W2979218211 hasRelatedWork W2023752803 @default.
• W2979218211 hasRelatedWork W2107472366 @default.
• W2979218211 hasRelatedWork W2327556405 @default.
• W2979218211 hasRelatedWork W2373658663 @default.
• W2979218211 hasRelatedWork W2586998360 @default.
• W2979218211 hasRelatedWork W2755681467 @default.
• W2979218211 hasRelatedWork W3005384069 @default.
• W2979218211 hasRelatedWork W3208072607 @default.
• W2979218211 hasRelatedWork W3215771247 @default.
• W2979218211 hasRelatedWork W768467596 @default.
• W2979218211 hasVolume "110" @default.
• W2979218211 isParatext "false" @default.
• W2979218211 isRetracted "false" @default.
• W2979218211 magId "2979218211" @default.
• W2979218211 workType "article" @default.