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- W2979303929 abstract "Abstract The first example of bifunctional oxindole‐chromone C3 synthon directed organocatalytic cascade cycloaddition reaction is developed, serving as a fruitful strategy for the facile access of optically active tetrahydrocyclopenta[b]chromanone bearing one spirooxindole with five contiguous stereocenters. All the products are smoothly obtained with up to 83% yield, >20:1 d.r. and >99% ee. This is also the first asymmetric catalytic construction of tetrahydrocyclopenta[b] chromanone and tetrahydrocyclopenta[b]chromanone‐spirooxindole scaffold, thus to facilitate the search for new bioactive entities. magnified image" @default.
- W2979303929 created "2019-10-18" @default.
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- W2979303929 date "2019-10-22" @default.
- W2979303929 modified "2023-10-14" @default.
- W2979303929 title "Oxindole‐chromones C3 Synthons Directed Stereocontrolled Construction of Five Contiguous Stereocenters on Spiro[tetrahydrocyclopenta[b]chromanone‐oxindole]s" @default.
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- W2979303929 doi "https://doi.org/10.1002/adsc.201901091" @default.
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