FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2979319669> ?p ?o ?g. }

• W2979319669 abstract "Abstract Abstract 4168 Background: Primary Pulmonary MALT lymphoma represents 15–20% of Extranodal Marginal Zone Lymphomas of Mucosa Associated Lymphoid Tissue (MALT). In contrast to the more common gastric MALT lymphoma, natural history, prognosis and treatment outcomes for primary pulmonary MALT lymphoma are not well defined. Herein, we report a single institution experience. Methods: Consecutive patients with primary pulmonary MALT lymphoma registered in the Mayo Clinic Lymphoma Database, which includes all consenting patients with lymphoma seen at Mayo Clinic Rochester, were reviewed for clinical features, treatment outcome progression free survival (PFS) and overall survival (OS). The pathology for all patients was centrally reviewed by hematopathologist and the diagnoses were based on WHO lymphoma classification criteria. PFS and OS were assessed using the Kaplan–Meier method and the Cox proportional hazard model was used to assess the impact of variables on PFS and OS. Results: Between December 1986 and June of 2009, ninety-seven patients with primary pulmonary MALT lymphoma were enrolled. The median age at diagnosis was 63 years (range 31–87). There were 43 (44%) males. The initial presentation was a unilateral pulmonary lesion (n=47, 48%), bilateral pulmonary lesions (n=41, 42%), and pulmonary lesion with intrathoracic lymphadenopathy (n= 4, 4%). Bone marrow involvement and presence of B symptoms were 4, 4% and 5, 5%, respectively. International Prognostic Index (IPI) was 0–1, 2–3 and 4–5 in 69, 25 and 1 patient(s) respectively. The median follow-up was 10.4 years. The estimated median OS was 13. 6 years and the median PFS was 5.5 years (Figure). In a multivariate analysis, age >60 (p=0.02) and ECOG PS>2 (p=0.01) were associated with shortened survival. The IPI and age adjusted IPI were not predictive of overall survival. The treatment outcomes for the most common treatment modalities are summarized in the Table below. The median PFS of the 38% of patients who had a complete surgical resection was excellent at 11.2 years; whereas for observed patients with residual disease after biopsy was 3.2 years. Only 8 patients received single agent rituximan with relatively low response rate. Summary: The prognosis of primary pulmonary MALT lymphoma is favorable, with a median survival of over 13 years. In patients with resectable disease, surgery alone is associated with excellent disease control. Further prospective studies are needed to define the optimal treatment of primary pulmonary MALT lymphoma. Disclosures: No relevant conflicts of interest to declare." @default.
• W2979319669 created "2019-10-18" @default.
• W2979319669 creator A5004152557 @default.
• W2979319669 creator A5020077278 @default.
• W2979319669 creator A5024819739 @default.
• W2979319669 creator A5025688165 @default.
• W2979319669 creator A5030603735 @default.
• W2979319669 creator A5048644166 @default.
• W2979319669 creator A5052260788 @default.
• W2979319669 creator A5059729547 @default.
• W2979319669 creator A5061713890 @default.
• W2979319669 creator A5064206924 @default.
• W2979319669 creator A5064576471 @default.
• W2979319669 creator A5071201232 @default.
• W2979319669 creator A5074099210 @default.
• W2979319669 creator A5076892547 @default.
• W2979319669 creator A5082719040 @default.
• W2979319669 date "2010-11-19" @default.
• W2979319669 modified "2023-09-27" @default.
• W2979319669 title "Primary Pulmonary MALT Lymphoma: Clinical Characteristics and Treatment Outcomes – Single Institution Experience" @default.
• W2979319669 doi "https://doi.org/10.1182/blood.v116.21.4168.4168" @default.
• W2979319669 hasPublicationYear "2010" @default.
• W2979319669 type Work @default.
• W2979319669 sameAs 2979319669 @default.
• W2979319669 citedByCount "1" @default.
• W2979319669 crossrefType "journal-article" @default.
• W2979319669 hasAuthorship W2979319669A5004152557 @default.
• W2979319669 hasAuthorship W2979319669A5020077278 @default.
• W2979319669 hasAuthorship W2979319669A5024819739 @default.
• W2979319669 hasAuthorship W2979319669A5025688165 @default.
• W2979319669 hasAuthorship W2979319669A5030603735 @default.
• W2979319669 hasAuthorship W2979319669A5048644166 @default.
• W2979319669 hasAuthorship W2979319669A5052260788 @default.
• W2979319669 hasAuthorship W2979319669A5059729547 @default.
• W2979319669 hasAuthorship W2979319669A5061713890 @default.
• W2979319669 hasAuthorship W2979319669A5064206924 @default.
• W2979319669 hasAuthorship W2979319669A5064576471 @default.
• W2979319669 hasAuthorship W2979319669A5071201232 @default.
• W2979319669 hasAuthorship W2979319669A5074099210 @default.
• W2979319669 hasAuthorship W2979319669A5076892547 @default.
• W2979319669 hasAuthorship W2979319669A5082719040 @default.
• W2979319669 hasConcept C126322002 @default.
• W2979319669 hasConcept C141071460 @default.
• W2979319669 hasConcept C159654299 @default.
• W2979319669 hasConcept C203014093 @default.
• W2979319669 hasConcept C207103383 @default.
• W2979319669 hasConcept C2778453870 @default.
• W2979319669 hasConcept C2778476033 @default.
• W2979319669 hasConcept C2778559949 @default.
• W2979319669 hasConcept C2778563104 @default.
• W2979319669 hasConcept C2779338263 @default.
• W2979319669 hasConcept C2779526237 @default.
• W2979319669 hasConcept C2779851268 @default.
• W2979319669 hasConcept C2779921676 @default.
• W2979319669 hasConcept C44249647 @default.
• W2979319669 hasConcept C50382708 @default.
• W2979319669 hasConcept C71924100 @default.
• W2979319669 hasConcept C90924648 @default.
• W2979319669 hasConceptScore W2979319669C126322002 @default.
• W2979319669 hasConceptScore W2979319669C141071460 @default.
• W2979319669 hasConceptScore W2979319669C159654299 @default.
• W2979319669 hasConceptScore W2979319669C203014093 @default.
• W2979319669 hasConceptScore W2979319669C207103383 @default.
• W2979319669 hasConceptScore W2979319669C2778453870 @default.
• W2979319669 hasConceptScore W2979319669C2778476033 @default.
• W2979319669 hasConceptScore W2979319669C2778559949 @default.
• W2979319669 hasConceptScore W2979319669C2778563104 @default.
• W2979319669 hasConceptScore W2979319669C2779338263 @default.
• W2979319669 hasConceptScore W2979319669C2779526237 @default.
• W2979319669 hasConceptScore W2979319669C2779851268 @default.
• W2979319669 hasConceptScore W2979319669C2779921676 @default.
• W2979319669 hasConceptScore W2979319669C44249647 @default.
• W2979319669 hasConceptScore W2979319669C50382708 @default.
• W2979319669 hasConceptScore W2979319669C71924100 @default.
• W2979319669 hasConceptScore W2979319669C90924648 @default.
• W2979319669 hasLocation W29793196691 @default.
• W2979319669 hasOpenAccess W2979319669 @default.
• W2979319669 hasPrimaryLocation W29793196691 @default.
• W2979319669 hasRelatedWork W1913144017 @default.
• W2979319669 hasRelatedWork W2079556447 @default.
• W2979319669 hasRelatedWork W2085216884 @default.
• W2979319669 hasRelatedWork W2123369918 @default.
• W2979319669 hasRelatedWork W2309906277 @default.
• W2979319669 hasRelatedWork W2347633991 @default.
• W2979319669 hasRelatedWork W2391152477 @default.
• W2979319669 hasRelatedWork W2391257761 @default.
• W2979319669 hasRelatedWork W2415994238 @default.
• W2979319669 hasRelatedWork W2528665829 @default.
• W2979319669 hasRelatedWork W2557688980 @default.
• W2979319669 hasRelatedWork W2585162903 @default.
• W2979319669 hasRelatedWork W2601319998 @default.
• W2979319669 hasRelatedWork W2606158293 @default.
• W2979319669 hasRelatedWork W2979352407 @default.
• W2979319669 hasRelatedWork W3028903917 @default.
• W2979319669 hasRelatedWork W3031357281 @default.
• W2979319669 hasRelatedWork W3093940434 @default.
• W2979319669 hasRelatedWork W3164541529 @default.
• W2979319669 hasRelatedWork W3170850484 @default.
• W2979319669 isParatext "false" @default.
• W2979319669 isRetracted "false" @default.

• next