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- W2979351013 startingPage "5029" @default.
- W2979351013 abstract "Alcohol-related liver disease (ALD) is caused by over-consumption of alcohol. ALD can develop a spectrum of pathological changes in the liver, including steatosis, inflammation, cirrhosis, and complications. Autophagy is critical to maintain liver homeostasis, but dysfunction of autophagy has been observed in ALD. Generally, autophagy is considered to protect the liver from alcohol-induced injury and steatosis. In this review, we will summarize novel modulators of autophagy in hepatic metabolism and ALD, including autophagy-mediating non-coding RNAs (ncRNAs), and crosstalk of autophagy machinery and nuclear factors. We will also discuss novel functions of autophagy in hepatocytes and non-parenchymal hepatic cells during the pathogenesis of ALD and other liver diseases." @default.
- W2979351013 created "2019-10-18" @default.
- W2979351013 creator A5022335283 @default.
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- W2979351013 creator A5057732137 @default.
- W2979351013 creator A5058637832 @default.
- W2979351013 creator A5091793236 @default.
- W2979351013 date "2019-10-11" @default.
- W2979351013 modified "2023-10-16" @default.
- W2979351013 title "Autophagy, Metabolism, and Alcohol-Related Liver Disease: Novel Modulators and Functions" @default.
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